This application report presents a simple guideline for achieving high density cultures of Chinese Hamster Ovary (CHO) cells using any of New Brunswick's autoclavable stirred-tank reactors.
This application report presents a simple guideline for achieving high density cultures of Sf-9 insect cells using any New Brunswick autoclavable stirred-tank reactors.
The objective of this study was to compare New Brunswick
CelliGen BLU single-use packed-bed bioreactor
and the traditional glass vessel counterpart used in New
Brunswick CelliGen 310. Alkaline phosphatase (ALKP)-
secreting Chinese Hamster ovary (CHO) cells were used
to measure ALKP production in each bioreactor. Overall,
the results from these comparisons suggest that there is
no significant difference between the reusable and singleuse
FibraCel basket systems for bench-scale production
of recombinant proteins. Productivity of cells and collection
of secreted proteins will not be hindered by the
implementation of single-use bioreactor systems.