Who Was First?

08/10/18

PCR was a milestone in biological research as it opened the door to many possibilities for gene manipulation and detection. The concept of PCR was put to work in 1985 by Kary Mullis. The invention was awarded by the Nobel Prize in Chemistry in 1993 [1].

Eppendorf Cycler History

Remember the time when heating and cooling was done by tap water? When samples needed to be secured by mineral oil? Or when 2 °C/s ramp rates were super-fast?

PCR machines have a history and the technical progress over the last nearly 30 years is impressing. Today, gradient functions, different heating ramps, heated lids, or connectivity are standard.

[1] The Journal of American Science, 1(3), 2005, Ma, Development of Polymerase Chain Reaction (PCR)