Bioprocess Systems for Perfusion Process Development at Small and Bench Scale

Lab Academy 20. May 2019

Perfusion cell culture processes help saving lab space, increasing volumetric productivity, achieving more consistent product quality, and improving production of less stable proteins. Experimentation at small and bench scale is crucial for the cost-efficient development of bioprocesses, which then can be transferred to larger production volumes.

In this webinar we present cell retention technologies suitable for small and bench scale bioprocessing. We show a case study of an ATF-based CHO cell perfusion process at a working volume of 1 L.

Learning Objectives:

Connection of an ATF-2 cell retention device with Eppendorf bioprocess systems
Bioprocess system technical requirements and configurations
Analysis of process performance: Cell growth, metabolite concentrations, and product formation
Other cell retention technologies, including packed-bed bioreactors and microcarrier spin filters

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Bioprocess Systems for Perfusion Process Development at Small and Bench Scale