TH | THB
Logged in as::
TH | THB
You are about to leave this site.
Please be aware that your current cart is not saved yet and cannot be restored on the new site nor when you come back. If you want to save your cart please login in into your account.
Genome Editing / CRISPR
Prokaryotic and eukaryotic cells
Genetic engineering terms the targeted modifications of genetic information of living organisms/cells. Genome editing stands for targeted engineering by using specifically designed nucleases. The recent CRISPR/ Cas-9 method uses RNA-guided nuclease. That makes the process faster, easier and more specific compared to other gene editing methods. Since the DNA-binding element is RNA it is simple and cheap to manipulate and it allows sequence specific programming. The high targeting efficiency, results in significant time saving, e.g., for the generation of knockout mice. In basic research CRISPR is mainly used in cell line engineering and animal genetic engineering (e.g. of disease models) to investigate gene function.