You need everything? Discover our most versatile solution for mixing, heating, and cooling of samples – proven and tested in thousands of labs worldwide.
Learn more: Video – Versatility of the Eppendorf ThermoMixer®
• All-in-one versatile device: Mixing, heating, and cooling of 100 µL – 50 mL tubes, MTP/DWP/PCR-plates, or cryovials (water-free, automated cell-thawing)
• Optimized temperature transfer for plates: Dedicated form-fitting blocks for DWP (96 well, 500/1000 µl) and PCR plates (96/384 well)
• Block homogeneity assured: Serial number-specific temperature test certificate, block-specific calibration possible, and IQ/OQ GxP service available
• Improved mixing results: Up to 3,000 rpm at a wide 3 mm orbit (2DMix-Control)
• Tool-free block exchange within seconds: Eppendorf QuickRelease function and automatic block recognition
• Condensation protection inside tubes and improved block homogeneity: Optional ThermoTop® heated lid with block-type specific heating for SmartBlocks up to 2.0 mL
• Parallel incubation at a different temperature: Optional SmartExtender for up to 12 x 1.5 mL tubes e.g., for enzymatic reactions
• Speed up your tasks: 5 keys for common programs plus 15 additional, storable programs (freely definable, multi-parameter)
• Proven design for longevity: Robust design and LCD display – ready for teaching labs and reliable operation for years to come
• Supports sustainability targets: Sustainability score validated by NGO My Green Lab® and certified with ACT® label
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Eppendorf ThermoMixer® C
Eppendorf ThermoMixer C can be equipped with different SmartBlocks
Eppendorf ThermoMixer C with SmartBlock 1.5 mL
Eppendorf ThermoMixer® C - One device for all your lab´s mixing tasks
Discover our most versatile solution for mixing, heating, and cooling of samples - Selection of compatible SmartBlocks
Easy and reliable operation for years to come
Robust design and LCD display – proven and tested since years in thousands of labs globally
Improve your mixing and tempering results
2DMix-Control: Up to 3,000 rpm at a wide 3 mm orbit – even for MTP or 384-well PCR plates
Optimized temperature transfer for plates
Dedicated form-fitting SmartBlocks for deep-well (96 well, 500 or 1000 µl) and PCR plates (96/384 well) ensure fast temperature transfer from the block to your samples
Eppendorf ThermoMixer C with ThemoTop
Quando o ThermoTop é colocado no instrumento, o aquecimento inicia imediatamente. A temperatura se adapta otimamente ao teste de temperatura para assegurar que não afeta negativamente a amostra. Não há oportunidade para a formação de gotículas de condensação.
Missing a second incubation temperature?
Optional SmartExtender: Up to 12x1.5 mL tubes, compatible with all SmartBlocks - for example for parallel enzymatic reactions.
Standardized and water-free cell thawing with the optional SmartBlock cryo thaw
Contamination protection, standardization, and versatilty needed? Convert your Eppendorf ThermoMixer® C (used with Eppendorf CryoStorage Vials here) into a powerful alternative to hand-/water bath warming or dedicated cell-thawing devices
Easy tube transfer and synchronized start of reactions
Optional Eppendorf Transfer Rack - For Eppendorf SmartBlocks 0.5, 1.5, and 2.0 mL
Eppendorf SmartBlock Removal (Step 1)
Passo 1: o mecanismo Eppendorf QuickRelease facilita e agiliza a troca de blocos. Basta pressionar a alavanca na parte frontal do bloco e o bloco será trocado em apenas alguns segundos e sem o uso de ferramentas.
Eppendorf SmartBlock Removal (Step 2)
Passo 2: o mecanismo Eppendorf QuickRelease facilita e agiliza a troca de blocos. Basta pressionar a alavanca na parte frontal do bloco e o bloco será trocado em apenas alguns segundos e sem o uso de ferramentas.
Eppendorf SmartBlock Removal (Step 3)
Passo 3: o mecanismo Eppendorf QuickRelease facilita e agiliza a troca de blocos. Basta pressionar a alavanca na parte frontal do bloco e o bloco será trocado em apenas alguns segundos e sem o uso de ferramentas.
Eppendorf ThermoMixer C: Sustainability rating by ACT
Independent sustainability certification needed? The ACT label of My Green Lab for Eppendorf ThermoMixer C
ThermoMixer_C SmartBlock_15mL angle view
Eppendorf ThermoMixer with SmartBlock 15 mL: Incubation and mixing with 15 mL conical tubes (up to 8 vessels)
ThermoStat C SmartBlock: PCR 96, total angle
Eppendorf ThermoMixer with SmartBlock PCR 96: Incubation and mixing for 96 well PCR plates (skirted, semi-skirted, and non-skirted)
Eppendorf ThermoMixer C with 5 mL tubes
Eppendorf ThermoMixer C with SmartBlock 5 mL: Incubation and mixing for 5 mL vessels
ThermoMixer_C SmartBlock_plate_total_angle
Eppendorf ThermoMixer C with SmartBlock Plates
ThermoMixer C lid, plate
Eppendorf Thermomixer C with SmartBlock and lid: The lid reduces loss of temperature as well as risk of contamination when using open vessels.
ThermoMixer C Scientist in lab with ThermoTop
Trouble with condensation? The Eppendorf ThermoTop heats from the top to reduce potential condensation within the vessel lids
Eppendorf ThermoMixer® - Change comes quickly, take advantage of our versatility
You need everything? The Eppendorf ThermoMixer C combines excellent mixing performance with excellent temperature control to ensure complete, dependable and reproducible test results. Improve your assay results by mixing and incubating samples at the same time. The Eppendorf ThermoMixer C convinces users with its quick and easy-to-exchange SmartBlocks for all common lab vessels, new and improved program functions, and high level of stability for every mixing frequency. There is almost no limit to the variety of applications waiting for you!
Product Information
Discover our most versatile solution for mixing, heating, and cooling of samples. Accessories include a wide selection of SmartBlocks e.g., form-fi tting DWP-blocks for fast tempering of samples, a block for controlled, water-free cell thawing, a heated lid to prevent condensates inside vessel lids (ThermoTop®), or the SmartExtender to incubate 1.5 ml tubes at a different temperature than the main block.
Thermo-Mixer-C-SB-1.5ml
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Learn more about sustainability at Eppendorf - incl. how to recognize a sustainable PCR thermocycler
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Product Information
Looking for a reliable lab partner for the years to come?
Eppendorf thermomixers are based on almost 80 years of experience developing shaking lab devices and thousands of labs worldwide using them. You'll find Eppendorf thermomixers still running strong after tireless performance over many years.
• Robust design and LCD display – ready for teaching labs and reliable operation
• Belt-less drive – no need for repeated and costly belt exchanges
• Easily run 10 years and longer with proper maintenance and service
• High-quality materials for high chemical resistance and corrosion resistance
• Serial number-specific temperature test certificate
• Block-specific calibration possible
• Technical and applicational support worldwide
• Made in Hamburg/Germany
Is your sample really mixed? – 2DMix-Control with 3 mm orbit up to 3,000 rpm
When mixing samples, we often just assume homogenization without verification, as checking is typically difficult. However, Eppendorf's decades of thermomixer development and customer feedback show that mixing performance can vary significantly with different parameters. The 2DMix-Control technology provides controlled, circular mixing with a 3 mm diameter and speeds up to 3,000 rpm. This is particularly beneficial for small tube or plate formats and challenging samples, where a large orbit and high RPM may be necessary (see link below).
Learn more: Influence of RPM and orbit on mixing results in 96- and 384-well plates
Fast temperature transfer for plates needed? – Form-fitting SmartBlocks
Have you measured your sample's temperature profile over time? You might be surprised by how much it can deviate from the setpoint and how long it can take to reach the target temperature – despite fast heating or cooling rates which always refer to the block and not the sample temperature.
The temperature profile of a sample is influenced by the heat transfer efficiency. For this reason, tube-specific thermoblocks contact all sides of the tube except the lid to enhance transfer efficiency. For plates, two thermoblock types exist: flat-bottom and form-fitting blocks akin to PCR cyclers.
Form-fitting blocks, like SmartBlocks for deep-well (96 well, 500 or 1000 µl) and PCR plates (96/384 well), enable rapid temperature transfer, ensuring the target temperature is reached quickly, even in short protocols (see exemplary comparison of thermal images after 5 min of incubation on the right).
Tip: If you are planning mixing tasks using DWP or PCR plates, measure the temperature profile, compare it with your target profile and consider form-fitting blocks.
Tool-, screw- and adjustment-free block exchange within seconds – Quick Release
You don't want to waste time struggling with tight and tiny screws, unplugging fragile cables, hunting for lost tools, or manually changing block settings? While many thermomixers claim "easy block exchange", the full process is usually never shown in videos – for good reasons.
Eppendorf's Quick Release function simplifies this: just press the lever to swap insulated SmartBlocks and the device automatically recognizes the new format. You're ready for new mixing tasks in seconds.
Tip: If you are planning to exchange thermoblocks regularly in your next mixer, check the operating manual or try the block exchange yourself for your next thermomixer. You would be surprised how easy or difficult it can be – depending on your choice.
Video: 1, 2, done - SmartBlock exchange within seconds
Consistent sample concentrations over time and comparability between samples in different block locations – ThermoTop heated lid
Condensation can form inside vessels depending on temperature, time, and RPM, leading to fluctuations in sample concentration. It also means the concentration may not even be stable over time as condensate droplets form and drip back into the sample. Complexity is added when comparing vessels or wells located centrally in the thermoblock with those at the periphery. Thus, condensation increases variance in experimental outcomes, necessitating more experiments to achieve statistical significance.
The optional ThermoTop heated lid offers block-type specific heating for SmartBlocks up to 2.0 mL, providing effective condensation protection without a need for manual adjustments and sample overheating. It ensures consistent sample concentrations over time and further improves comparability between samples in different block locations.
Tip: Consider a thermomixer with a heated lid with automatic block recognition and automatic temperature adjustment for low volume tubes or different plate formats. Manual height or temperature adjustment is not only time-consuming but may also lead to undetected overheating of samples.
Learn more: Condensation protection with the ThermoTop heated lid
Parallel incubation at a different temperature – SmartExtender
You want even more flexibility? How about a second incubation temperature or 50 % more capacity for incubating your 1.5 mL tubes?
The optional SmartExtender accommodates up to 12 x 1.5 mL tubes and is compatible with all Eppendorf SmartBlocks – for example for simultaneous enzymatic reactions at 37 °C or 95 °C. The independent heating function allows concurrent use with an Eppendorf SmartBlock, while preserving its heating, cooling, and mixing capabilities.
Easy tube transfer and synchronized start of reactions – Transfer Rack
Need a 60-second incubation for 24 samples tubes simultaneously? The Eppendorf Transfer Rack facilitates safe and easy transfer of up to 24 tubes in parallel to or from the Eppendorf SmartBlock, ensuring consistent reaction conditions for all samples. Compatible with SmartBlock sizes of 0.5 mL, 1.5 mL, and 2.0 mL, the Transfer Rack is included as standard. It holds up to 24 microtubes, allowing convenient transfer of hot vessels without risk of burns.
Tip: Use the Transfer Rack lid for quick inversion of all tubes or to ensure equal fit in the SmartBlock with a quick press.
More support for your PCR-workflow
In addition to form-fitting SmartBlocks for 96- and 384-well PCR plates and the ThermoTop® for efficient temperature transfer (see above), we offer additional accessories for your mixing tasks.
• Stackable PCR-Rack
• PCR-Cooler in pink or blue: Keeps a 96-well PCR plate cold for more than an hour at 0 °C (2 h precooling at -20 °C) and changes color when temperature exceeds 7 °C (see color change from bottom to top in the image on the right)
Want to speed up your tasks?
You don't want to spend your time navigating through programs or doing extensive thermomixer trainings for your new lab members?
Simply start one of the five pre-programmed protocols by the quick start keys or just define your own program (15 storable, freely definable, multi-parameter). The intuitive user interface supports you with five operational languages.
Supports your sustainability targets
Eppendorf is committed to accountability, consistency and transparency – the three principles of the ACT® label – to reduce its environmental impact and provide its customers with high-quality, sustainable products.
In addition to many other products Eppendorf offers, the sustainability score has been validated by the NGO My Green Lab® and the Eppendorf ThermoMixer® C has been certified with an ACT label.
Learn more: Sustainability aspects of the Eppendorf ThermoMixer C
Annoyed by uncomfortable handling?
Ergonomics goes far beyond the »ergonomically designed chair«. Eppendorf already started to optimize laboratory devices with regard to ergonomics in the early 1970s.
In 2003, we started the PhysioCare Concept®, focusing on ergonomic liquid handling devices like our pipettes.
Nowadays, the Eppendorf PhysioCare Concept has been broadened to include further laboratory products as a holistic solution to harmonize the workflow in your laboratory with your health and well-being, e.g. for the Eppendorf ThermoMixer:
• Eppendorf QuickRelease for easy and fast block exchange
• Insulated SmartBlock for safe gripping / no burning of fingers
• Direct keys for convenient handling
• Small footprint to enable position in direct arm reach at your bench
• Standardized »user-interface concept« for intuitive handling of devices
Learn more: The Eppendorf PhysioCare Concept
Be confident beyond your sample safety with VisioNize®
Lab Suite
Keep track of what matters most in your lab – anytime, anywhere. VisioNize Lab Suite provides a reliable digital monitoring solution for your laboratory equipment, helping you to increase sample security and compliance needs.
Monitor all key device parameters such as temperature, speed, and device interactions in real time. Stay informed about the status of your experiments and receive instant notifications via app, email, or SMS for important events – like program completion.
Easily export parameters and event data for documentation or analysis, supporting your compliance and research needs.
Experience peace of mind with continuous monitoring and real-time alerts.
Find out more about how VisioNize Lab Suite can support your lab's digital journey!
Disposal of packaging
The packaging of the mixer contains different materials, this includes cardboard, a plastic dust cover, and some foam parts. Recycling of materials becomes more and more important every day: Are you aware that nearly all cardboard material is recycled in Europe? Our mixer packaging cardboard material consists of ca. 60 % recycling material. Please support the global sustainability initiative of recycling valuable raw material by also collecting the thermomixer cardboard packaging material and disposing of it in the appropriate collection container at your organization. In respect to the plastic dust cover made of LD-PE and the foam parts, we recommend selecting a dedicated recycling partner where PE material can be recycled. We suggest you contact your local waste hauler or facility management team to understand the available recycling options for your organization.
Disposal of instrument
Our mixers last for many years, but if they need to be replaced, we kindly ask you to fulfill local requirements for disposal of these instruments. We strongly recommend a certified local recycling partner with experience in instruments with electronics. Keeping it "local" reduces the impact of transportation, and the "certified" aspect is recommended due to the safe and sustainable removal of specific parts.
Decontamination
This piece of equipment was used in a laboratory and/or was used to handle biological samples. Please keep in mind to adequately decontaminate the equipment which needs to be disposed. Check local requirements. For more information, get in contact with your local biosafety officer and/or waste officer. Check if your local recycling partner has special instructions and/or documentation requirements. You may also use the Eppendorf decontamination form sheet as guidance.
