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Multipette® M4 - Multi-Dispenser Pipette

Product Information

Say goodbye to tedious, time-consuming serial pipetting! The Multipette M4 pipette from Eppendorf is ideal for repetitive dispensing tasks in long series, eliminating the need for repeated liquid aspiration. Paired with Combitips® advanced dispenser tips, the Multipette effortlessly handles viscous, volatile or foaming liquids that pose challenges to traditional pipettes. The hermetically sealed tips in the Multipette/Combitips positive displacement pipetting system ensure a high level of safety when working with infectious, toxic, or radioactive liquids.

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Sets & Bundles (2)

Services (11)

Accessories (5)

Spare Parts (3)

    • 1-channel
    • 1 µL – 10 mL
    • incl. Combitips® advanced Box 2.0, Combitips® advanced assortment pack (1 tip of each size) and Pipette Holder 2
    More Product Details ...
    Catalog no. 4982000314
    3.340,00 DKK

      • 1-channel
      • 1 µL – 10 mL
      • incl. 1x Combitips® advanced 2.5 mL (green) tip and Pipette Holder 2
      More Product Details ...
      Catalog no. 4982000012
      3.210,00 DKK

      Product Information

      Technical Data



      Aspirate liquid once and dispense up to 100 times without tip refill

      The Multipette M4 mechanical multi-dispenser pipette allows you to aspirate liquid once and dispense up to 100 times, making it the ideal precision instrument for long, repetitive pipetting tasks, such as tube or plate filling, and aliquoting reagents. Liquid is aspirated and dispensed by positive displacement, which means there is no air cushion that may be affected by liquid sample properties. This ensures that the correct volume is always dispensed - regardless of the density, viscosity and volatility of the liquid.
      The matching Combitips® advanced and ViscoTip® positive displacement dispenser tips are automatically recognized - eliminating time consuming volume calculations - and are hermetically sealed to provide a high level of user, instrument and sample safety. Ideal for handling infectious, toxic or radioactive liquids.

      Eppendorf pioneered the Multipette/Combitips multi-dispenser system in 1978 and improved it several times since. It was the very first pipetting system allowing users to fill the tip once and dispense multiple times. The concept remains a driver for efficient liquid handling and a staple in many labs working with plates or series of tubes. In 2024, our Multipette M4 multi-dispenser was awarded the ACT® Environmental Impact Factor Label along with Combitips advanced dispenser tips, showcasing our dedication to eco-conscious manufacturing and assisting customers in taking environmentally informed purchase decisions.

      A repetitive pipette with advanced interface and sensor control for easy operation

      Step counter
      • Displays the number of executed dispensing steps

      Volume selection dial
      • 20 different volume settings for every size of Combitips advanced

      Motion sensor
      Even if a Combitips advanced dispenser tip is left attached, the Multipette M4 switches off when not in use to save power. When moved again, it switches back on automatically, while still “remembering” the number of executed dispensing steps for increased efficiency.

      Combitips advanced attachment sensor
      • Automatic Combitips advanced tip recognition and volume display
      • Ensures a secure connection between Combitips advanced and Multipette M4

      Make laborious, time-consuming serial pipetting tasks more comfortable

      With its easy-to-reach and easily adjustable volume selection dial, the Multipette M4 makes repetitive pipetting tasks manageable. A hand rest supports a relaxed, ergonomic hand position and ease-of-use, ensuring the Multipette M4 provides a greater level of comfort over the day.

      The ergonomically shaped operating lever both fills and dispenses the liquid, and also ejects theCombitips advanced dispenser tips, with one-handed operation.

      How to use a Multipette M4 repetitive pipette?

      The Multipette M4 is extremely easy to use: Just insert a compatible dispenser tip (Combitips advanced or ViscoTip) into the M4 while pushing the operating lever. The pipette automatically recognizes the tip size, and you can directly select the volume and steps needed for your application. The volume can even be changed between dispensing steps. Place the tip into the liquid sample and gently push the operating lever to aspirate the total volume to be dispensed. Push the operating lever once to trigger a reverse stroke needed to maximize accuracy. Afterwards, you can start dispensing into your target vessel(s) by pushing the operating lever slowly as far as it will go. Learn more in our Quick Start Guide.

      Convenient storage options for your multi-dispenser & pipettes

      Our Multipette M4 pipette holders for wall mounting or the Eppendorf Pipette Holder System can be affixed to virtually any surface or integrated with either our charging or non-charging manual pipette carousel stands. Alternatively, one Multipette M4 multi-dispenser can be stored in the Pipette Stand 2 by Eppendorf.

      Disposal of packaging and the dispenser at the end of its lifecycle

      The packaging of Multipette M4 dispensers contains different materials, including cardboard and plastic foil. Our Multipette packaging cardboard material consists of approx. 92 % recycling material. Please support the global sustainability initiative of recycling valuable raw material by collecting the cardboard and disposing of it in the appropriate collection container at your organization. In respect to the wrapping foils made of LD-PE, we recommend to select a dedicated recycling partner where PE material can be recycled.

      Eppendorf liquid handling instruments are designed for many years of use – should the need arise to dispose of your Multipette however, please note that it may potentially be contaminated and includes electronic components and a battery. Please contact your local biosafety officer and/or your local waste management for requirements and best practices concerning electronic and lab waste. You may use the Eppendorf Decontamination Certificate as guidance regarding possible documentation requirements.