How can I adjust my air-cushion pipette for challenging liquids, long tips, or higher/lower altitudes?

Upon manufacturing, pipettes are calibrated to distilled water. Eppendorf mechanical pipettes allow temporary user adjustments, beneficial for liquids with different physical properties than water (density, viscosity, surface tension, vapor pressure), or when capillary actions occur (e.g., with DMSO). Adjustments are also beneficial when atmospheric pressure changes due to altitude or when using non-standard pipette tips (e.g., epT.I.P.S. long). The adjusted pipette delivers the correct volume only for the liquid used during adjustment. Please be aware that variable mechanical pipettes turn into "fixed-volume pipettes" when being adjusted. That means they can only be adjusted to a specific liquid to one volume and not across the entire dispensing range. Research plus and Reference 2 pipettes feature an adjustment window where the change can be monitored. It can be set back to factory settings "0". For detailed procedures and examples, refer to the operating instructions and Application Note No. 198. In contrast to mechanical pipettes, the electronic Xplorer/Xplorer plus pipettes can be adjusted for the entire range of volume. Additionally, the electronic pipettes offer several options for adjusting the pipette in the "Options" menu, e.g. to 75 % ethanol, altitude, elongated tips. Furthermore, individual adjustments are possible, as 1-point, 2-point or 3-point settings. For more information see User Guide 036. Temporary user adjustments can be reset to manufacturer settings without recalibration.

How do I determine the volume values when calibrating gravimetrically?

The most common method involves measuring the mass of distilled water (whose physical properties are known) using a balance, and then converting the mass to a volumetric value. This means that the measurement values from the analytical balance are multiplied by the correction factor Z (see SOP pipettes). This adjustment accounts for the density of water at the specific temperature and the relevant air conditions.

What does EN ISO 8655 cover?

ISO 8655-2022 is the global standard for piston-operated volumetric apparatus (POVA), including pipettes, burettes, dilutors, dispensers, and manual precision syringes, as defined by the International Organization for Standardization (ISO). It ensures standardized performance for manufacturers, calibration providers, and users.It is structured in 10 chapters: ISO 8655-1: Terminology, general requirements and user recommendations ISO 8655-2: Pipettes ISO 8655-3: Burettes ISO 8655-4: Dilutors ISO 8655-5: Dispensers ISO 8655-6: Gravimetric reference measurement procedure ISO 8655-7: Alternative measurement procedures ISO 8655-8: Photometric reference measurement procedure ISO 8655-9: Syringes ISO 8655-10: User guidance, user qualification and POVA qualification.

What do the terms random error and systematic error mean in a pipette calibration?

In pipette calibration, random error and systematic error are two key concepts that help ensure accuracy and precision in measurements. Random Error refers to the variability in measurements when the same volume is dispensed multiple times. It is also known as imprecision and is determined by calculating the repeat standard deviation of 10 measurements. These errors tend to scatter around the true value and can be minimized by consistent technique and proper training. Systematic Error is the consistent deviation of the measured volume from the selected/true volume, also known as inaccuracy and is determined by establishing the mean value of 10 measurements. Systematic errors can arise from defective or misadjusted devices and need to be corrected through proper calibration and maintenance.

At which volumes should a variable pipette be calibrated?

According to the EN ISO 8655-2022 standard, three series of 10 measurements are used to calibrate a variable-volume pipette. The three test volumes are: 1. Nominal volume (the largest volume adjustable by the user, as determined by the manufacturer) 2. 50% of the nominal volume 3. 10% of the nominal volume, or the lower limit if the minimum is over 10%

What is the nominal volume of a variable pipette?

The nominal volume of a variable pipette is always its maximum volume. For a 100 - 1,000 µL pipette, this means 1,000 µL.

I very frequently work with different chemicals. Can I still perform pipette calibration using water?

As per EN ISO 8655-2022, pipette calibration, which involves checking liquid dispensed by the pipette on a balance, should always be performed using distilled or deionized water. If you are working with chemicals that have different properties than water, consider using the temporary adjustment to minimize errors as outlined in Application Note 198. In general, we recommend using direct displacement devices such as the Multipette M4/E3(x) for challenging liquids.

How are multi-channel pipettes tested?

According to ISO 8655-2022, every channel of a multi-channel pipette must be tested. While all channels need to be filled, only the channel being tested is measured. Due to the high number of measurements required (e.g., 240 measurements for an 8-channel pipette and 360 measurements for a 12-channel pipette), it is advisable to send the multi-channel pipette to a professional calibration lab. These labs are equipped with specialized balance setups that ensure all channels are filled while only one channel is measured at a time.

Is the pipette grease free of resins?

Yes, the pipette grease supplied by Eppendorf is free of resins.

Is a gravimetric test necessary after resetting the adjustment display to "0"?

From a technical point of view, a gravimetric test is not required. However, for certified laboratories a gravimetric test might be required for documentation purposes.

How many overnight cycles or total hours of UV irradiation can the Research plus withstand before any discoloration or change of the material will be visible?

We tested UV radiation under very intense conditions for 165 hours. There was no visible discoloration or change to the material. We recommend sterilizing Research plus pipettes with UV light 30 W at 254 nm and a distance of 60 cm.

Can the Research plus be autoclaved if the locking ring is installed to deactivate the spring loading?

Yes. The locking ring is made of PPS (polyphenylene sulfide) and therefore autoclavable (121 °C, 1 bar, 20 min).

Do I need to disassemble the Research plus before autoclaving?

No. It can be autoclaved in one piece (121 °C, 1 bar, 20 min).

Will water vapor enter the pipette while it is being autoclaved, causing water vapor to bead up on the inside of the numerical volume setting display?

Vapor will penetrate the inside of the pipette during autoclaving but this will not cause damage. We tested our pipettes with 175 autoclaving cycles (121 °C, 1 bar, 20 min). The number of tests chosen corresponds to an average of 5 years of use.

In part 3 of the operating manual of the Research plus, you recommend adjusting the volume setting from a higher value to a lower value. If required, the user should turn the value beyond the required value and then back again. What is the reason for such a recommendation?

For technical reasons, the results are generally more precise when a volume setting is carried out from a higher down to a lower value. This is valid for all manual pipettes.

How should the Research plus be decontaminated or disinfected?

Wipe the outer surface with disinfectant, DNA/RNA decontamination agent, or 70 % isopropanol or a commercially available disinfectant. Check the chemical resistance of the pipettes using the chemical resistance table (see download section at www.eppendorf.link/researchplus). After the exposure time of the disinfectant, rinse thoroughly with demineralized water. This step is especially important if subsequent decontamination, e.g., with UV-light or autoclaving, should be performed. The Research plus may be temporarily subjected to UV light under a sterile bench. We recommend the use of a Hg-lamp, 254 nm, 30 W. The distance between lamp and pipette should be approx. 60 cm. The Research plus is fully autoclavable.

How can I clean and maintain the Research plus?

The Research plus pipettes are easy to clean. Only the lower part should be cleaned on a regular basis in accordance with the frequency of use. The lower part of the single-channel and multi-channel Research plus pipettes can be removed easily as described in the operating manual of the Research plus or in our Application Note 198.

Is it possible to inactivate the spring-loaded tip cone of a single-channel pipette?

Yes, the delivery includes a locking ring to easily deactivate the spring-loaded tip cone. Disassemble the upper from the lower part of the pipette and push the locking ring onto the lower part from the top. Refer to the Operating Manual for an illustrated guide. This is useful for pipette tips not designed for Eppendorf pipette cones.

How often can I autoclave the Tip-Tub reagent reservoir (Order no. 0030058607), and what conditions should I use?

The Tip-Tub reagent reservoir (approx. 13.8 cm × 5.8 cm × 3.3 cm) is made entirely of polypropylene (reservoir and lid) and is autoclavable. Please note the following: Autoclave conditions: • Autoclave for 20 minutes at 121 °C and 1 bar overpressure. • Do not apply any force or weight on the product during autoclaving Preparation & positioning: • Remove all packaging including plastic foil before autoclaving. • We recommend autoclaving the Tip-Tub lying flat. It can also be autoclaved upside down, stacked, or placed upright in a glass vessel. Number of cycles: • The Tip-Tub can generally be autoclaved multiple times without loss of function. • As with all polypropylene labware, each autoclaving cycle stresses the material, so after repeated autoclaving (e.g., around 20–30 cycles) slight deformations or a “milky” lid may occur. These changes are typically only in appearance and do not affect the intended use of the product.

What is the difference between factory setting and user adjustment?

Eppendorf pipettes offer factory adjustment and temporary adjustment. The temporary adjustment is an easy way of adjusting the pipette temporarily to different conditions (e.g. pipetting a liquid with high density). The factory adjustment should be changed if the pipette was found to be out of specifications during calibration. Before adjusting, exclude other causes such as pipette handling, environmental errors, or worn-out parts.

How often should pipettes be calibrated?

The user determines the frequency of calibration. However, according to EN ISO 8655-2022 Part 1, calibration must be performed regularly and at a minimum, once per year. Routine tests should be performed more frequently, ideally at intervals shorter than those for calibration. The frequency of both calibration and routine tests should be established through a risk assessment. This assessment needs to consider factors such as the frequency of pipette use, the number of users, the aggressiveness of the liquids being dispensed, and the acceptable error limits set by the user. Additionally, any industry- or organization-specific frequency requirements must be adhered to.

What is reverse pipetting using an air-cushion pipette? Is there literature available?

Unlike forward pipetting, reverse pipetting involves pressing the pipette button to the second pressure point, allowing a greater volume to be aspirated into the tip. When dispensing liquid, there’s no pipette blow-out; instead, the residual liquid remains in the tip. This technique offers enhanced accuracy and precision for pipetting liquids with high viscosity or those prone to foam or produce bubbles. Eppendorf offers a variety of literature explaining the technique and proving application examples, such as the Userguide 020, several webinars, and YouTube videos.

What is pre-wetting using an air-cushion pipette, and is it volume-independent?

Regardless of the volume, the air cushion should be wetted by multiple filling and emptying of the tip before dispensing.

What are effective techniques for pipetting viscous liquids?

When pipetting viscous liquids, we recommend positive displacement instruments such as the Multipette (M4, E3, E3x). Those instruments offer the best dosing accuracy for viscous liquids due to the piston integrated into the tip. When handling viscous liquids with an air-cushion pipette (Research plus, Reference 2), be sure to pipette slowly and use reverse pipetting (see Userguide 020 or our extensive eBook on www.eppendorf.com/Pipetting-eBook for guidance). Additionally, adjust your pipette settings to account for differences in density by using the temporary adjustment. However, results will not match those achieved with a positive displacement device.

Are your pipettes free of nucleic acids?

We cannot guarantee that our pipettes are completely free of nucleic acids. While we maintain high standards of cleanliness and care during production, we do not implement specific measures to prevent nucleic acid contamination. To protect your samples from potential contamination, we recommend using positive displacement devices or filter tips, such as ep Dualfilter T.I.P.S. or ep Dualfilter T.I.P.S. SealMax.

When should I grease my Eppendorf pipettes?

The piston or cylinder in the lower part of the pipette should be relubricated after cleaning, decontamination, or exposure to grease-dissolving solutions such as organic solvents. Re-greasing your pipette after autoclaving is not necessary.

How should warm or cold liquids be pipetted?

Best Practices for Pipetting Warm or Cold Liquids: Warm and cold liquids can behave differently than those at room temperature, requiring adjustments in pipetting techniques. Temperature differences between the liquid and the pipette can affect the air cushion, resulting in inaccuracies and imprecision that may exceed permissible error limits. To achieve optimal results, ensure that the pipette, tips, liquid, and surrounding air are all at the same temperature. For enhanced accuracy and precision, consider using a positive displacement device like the Multipette M4 or E3/E3x.

Can the heat of my hand affect my pipetting result?

Modern pipettes address this issue by ensuring sufficient spatial separation between the piston and the handle. Additionally, the materials used in our pipettes support thermal shielding/isolation to prevent heat transfer from your hand (see Userguide 021).

Do Eppendorf pipettes always have to be kept in a stand or can they also be put down on the laboratory bench?

The pipette can be placed on the laboratory bench, but never with liquid inside the tip. In general, it is best to keep pipettes on the pipette carousel. When storing pipettes in a drawer, ensure the pipette does not come into contact with the drawer walls or other equipment, as this may damage the pipette when the drawer is opened or closed.

What material is my pipette made of and what chemicals is it resistant to?

Please refer to the Operating Manual on our homepage for information on material or chemical resistance before use. The Research plus and Reference 2 have separate chemical resistance sheets. Please note that aggressive chemicals used over a longer period of time may shorten the lifetime of the pipette.

My Research plus/Xplorer plus pipette with 20 µL has the color code "pearl white". Which tips should I use?

Eppendorf changed the color code of all 20 µL pipettes and epT.I.P.S. ® 384 tips to light pink. You can use light pink tips with your pipette in pearl white. As part of our service offering, we offer to convert 20 µL pipettes sent in to light pink free of charge. This avoids confusion with the appropriate tips.

text.skipToContent text.skipToNavigation

IN | INR

Sorry, we couldn't find anything on our website containing your search term.

Eppendorf Research^® plus

4-digit volume display on Eppendorf Research® plus mechanical pipettes

Eppendorf Research® plus manual pipette 4-digit display for easy and precise volume adjustment

Eppendorf Research® plus manual pipettes feature a temporary adjustment option for challenging liquid classes

The Pipette Carousel 2 carries up to six Eppendorf Research® plus pipettes

Eppendorf Research® plus multi-channel pipettes with 8 or 12 tip cones for PCR-strips and 96-well plates

Eppendorf Research® plus multi-channel pipette with 8 tips used to fill a deepwell plate

Eppendorf Research® plus 16 and 24-channel mechanical pipettes and 384-well plate

Fill 384-well plates with ease using Eppendorf multi-channel pipettes with 16 or 24 channels

Eppendorf multi-channel pipettes with 16 or 24 tip cones are ideal to dispense multiple samples in 384-well plates

Eppendorf multi-channel pipette with 24 tips dispensing liquid into agarose gel for gel electrophoresis

Male laboratory technician works at the bench with PCR, Eppendorf ThermoMixer® and dispenses liquid in a plate

Female Scientist using Eppendorf Research® plus Single-Channel Pipette

ACT label of sustainability certification for Eppendorf Research® plus pipette, 100-1000 µL (blue), single-channel, variable

Product Information

The Eppendorf Research plus is one of the safest and most ergonomic mechanical pipettes available. Meeting the highest needs of precision and accuracy while providing high flexibility via a large number of variants, the Research plus will become an indispensable companion in your lab. This micropipette is remarkably light, both in terms of weight and pipetting forces, which helps you to avoid hand and arm strain. The 16- and 24-channel pipette system combines proven concepts with new innovations and facilitates quick & easy manual pipetting in 384-well plates.

Show more Product Information

You will find additional download material at the bottom of this page

Product Information

Technical Data

Applications

Features

The light pipette for effortless pipetting

The Eppendorf Research plus mechanical pipette is the result of over 60 years of experience in liquid handling and is one of the most commonly used pipettes in the world. Thanks to the pioneering Eppendorf PhysioCare Concept ^®, the Research plus is highly ergonomic and protects your health in the laboratory. It features very low weight and operation forces, is extremely reliable, fully autoclavable and easy to use.
With a variety of options available, including single-channel pipettes with fixed or variable volume, multi-channel pipette options with 8, 12, 16 or 24 channels, and our Research plus Move It adjustable tip spacing multi-channel pipettes, we are confident that we can offer the right choice for your application.
It is a good feeling to know you are doing the right thing – to know you are working with one of the most renowned and advanced pipettes in the world. A spring-loaded tip cone, a temporary adjustment option, an improved volume display – and all that in a light, fully autoclavable pipette: That is the Eppendorf Research plus manual pipette. In 2021, the Research plus single-channel pipette line-up with variable volume has been certified with an ACT^® Environmental Impact Factor Label by the My Green Lab^® non-profit organization, making it the ideal choice for labs looking for more sustainable products.

Accoladed with a SelectScience Seal of Quality

The Research plus mechanical lab pipette was accoladed with a “Seal of Quality” by SelectScience^®. These seals are given to the top 0.1 % of products used in laboratories that have received more than 100 positive reviews on the esteemed SelectScience platform. The award is praised as providing invaluable insights for scientists and intends to help them choose the ideal lab product for their working environment.

Which level of flexibility and safety do you require?

Variable volume pipettes for highest flexibility
• Adjust dispensing volume within a range of 0.1 µL and 10 mL
• Selected volume is displayed in the large 4-digit volume display
• Quick and accurate volume settings
• Available as single-, 8-, 12-, 16- and 24-channel as well as Move It adjustable tip spacing pipettes

Fixed-volume pipettes for a fast and reliable workflow
• Work at a faster pace with fixed set volumes
• Reduce the chance of errors compared to a pipette with variable volume
• Fast and easy calibration
• Available as single-channel pipettes in 12 different variants
• Perfect for beginners and labs on a budget

Choose the correct pipette set for your application needs

Not all experiments are based on the same working conditions. Depending on the vessel type, you can choose from single-channel microliter pipettes that are ideal for tubes, and multi-channel pipettes better suited for plates.

• Tubes: Single-channel pipettes with fixed or variable volume
• 96- and 24-well plates: 8- and 12-channel pipettes
• 384-well plates: 16- and 24-channel pipettes
• Vessel type changes: Move It adjustable tip spacing pipettes

Fatigue-free and ergonomic pipetting

The Eppendorf Research plus microliter pipette is intuitive to operate, provides a perfect balance and minimizes operator strain and fatigue, developed in line with the Eppendorf PhysioCare Concept. The result is a light and well-balanced pipette, equipped with the unique spring-loaded tip cone and SoftEject features. Operating forces can be reduced even further by combining the Research plus 16- and 24- channel pipettes with the epT.I.P.S. 384 pipette tips with SoftAttach^® technology.

Spring-loaded tip cones for reliable tip fit and effortless attachment

Eppendorf pipettes with spring-loaded tip cone save you time and energy. With haptic feedback, all it takes is one gentle push-down for easy tip attachment. The spring limits the attachment forces and at the same time guarantees a reproducible and safe tip fit. This clever design provides increased user-to-user reproducibility and more consistent results between different lab members. All micropipettes from Eppendorf up to 1,000 µL (except Move It 300 µL models) are equipped with the spring-loaded tip cone feature.

SoftEject technology reduces tip ejection forces by 50 %

All non-adjustable multi-channel pipettes from Eppendorf use the innovative SoftEject technology to ensure that during each single tip ejection stroke, the outside tips eject before the inside tips. This is not noticeable to the user but reduces tip ejection forces by 50 %. You just lightly press the ejection button once and the tips are automatically ejected in succession.

Speed up your workflows with mechanical multi-channel pipettes

Do you need to easily and quickly fill a 24-, 96- or even 384-well microplate? With the lightweight Eppendorf Research plus 8-, 12-, 16- and 24-channel pipettes you can perform high volume precision work faster. The spring-loaded tip cones help you to load multi-channel tips quickly and securely without a need for rocking. Get extremely consistent sample pickup across all channels and maximize user-to-user reproducibility for more consistent results among members of the lab.

96-well plates
Easily fill 96-well plates with Research plus 8- or 12-channel pipettes featuring a cone distance of 9 mm. Our 1,200 µL volume pipettes are ideal for filling deepwell plates.

Choose epT.I.P.S. pipette tips for 9 mm spacing

384-well plates
Choose the Research plus 16- or 24-channel pipettes or selected Move It adjustable tip spacing pipette models featuring cone distances of (min.) 4.5 mm for applications in 384-well plates. Fill a complete row or column to start 16 or 24 reactions simultaneously in just one step.

Choose epT.I.P.S. 384 pipette tips for 4.5 mm spacing

Fast and efficient pipetting into 384-well plates

Do you need an efficient manual pipetting method for 384-well plate applications? The 16- and 24- channel pipettes from Eppendorf make working with 384-well plates convenient, ergonomic and safe.

Your benefits:
• Tedious alternate well pipetting with 8- or 12-channel pipettes is a thing of the past
• Processing one 384-well plate instead of four 96-well plates improves pipetting efficiency since the number of pipetting steps is reduced by 50 %
• Start 16 or 24 reactions simultaneously for equal starting conditions
• Avoid accidental well misidentification and repeating of experiments
• epT.I.P.S. 384 pipette tips are designed in perfect harmony with these microliter pipettes

epT.I.P.S. 384 with SoftAttach^® technology for 16- and 24-channel pipettes

For the first time, pipette tips are equipped with elastic forming groves. They allow the tips to stretch as much as the shape of the tip cone predefines. Meanwhile, the tip attachment and ejection forces are greatly reduced. With this latest expression of the Eppendorf PhysioCare Concept, this system enables a perfect tip seal while operating forces are reduced to a minimum.

Your benefits:
• Reliable tip fit and tightness
• Smooth and even tip attachment
• Tip attachment forces reduced by 40 % per cone compared to 8- and 12-channel pipettes
• Reduced ejection forces
• Perfect tip alignment due to extraordinary coaxiality for safe plate maneuvering and liquid transfer
• Extremely fine tip shape to perfectly hit all 384 wells

Disposal of packaging and the pipette at the end of its lifecycle

The packaging of Eppendorf pipettes & dispensers contains different materials, this includes cardboard, plastic foil, as well as pipette tip boxes. Our pipette packaging cardboard material consists of approx. 77 % recycling material. Please support the global sustainability initiative of recycling valuable raw material by collecting the cardboard and disposing of it in the appropriate collection container at your organization. In respect to the wrapping foils made of LD-PE, we recommend to select a dedicated recycling partner where PE material can be recycled.

Eppendorf liquid handling instruments are designed for many years of use – should the need arise to dispose of an instrument however, please note that it may potentially be contaminated. Therefore, recycling of pipettes or dispensers may be challenging. Please contact your local biosafety officer and/or your local waste management. In many countries, this waste must be burned due to legal restrictions. We recommend you to work with a certified local recycling partner with experience in lab waste however to examine your options.

Read Less

Technical data and specifications of the Eppendorf Research^® plus pipette set, including the number of channels, volume ranges, random and systematic error, autoclavability, and more.

Specifications	Eppendorf Research^® plus - 3123000012	Eppendorf Research^® plus - 3123000020	Eppendorf Research^® plus - 3125000010	Eppendorf Research^® plus - 3125000028	Eppendorf Research^® plus - 3125000079	Eppendorf Research^® plus - 3125000087	Eppendorf Research^® plus - 3123000098	Eppendorf Research^® plus - 3123000039	Eppendorf Research^® plus - 3125000095	Eppendorf Research^® plus - 3125000109	Eppendorf Research^® plus - 3123000047	Eppendorf Research^® plus - 3125000036	Eppendorf Research^® plus - 3125000044	Eppendorf Research^® plus - 3123000055	Eppendorf Research^® plus - 3123000101	Eppendorf Research^® plus - 3125000052	Eppendorf Research^® plus - 3125000060	Eppendorf Research^® plus - 3123000063	Eppendorf Research^® plus - 3125000214	Eppendorf Research^® plus - 3125000222	Eppendorf Research^® plus - 3123000144	Eppendorf Research^® plus - 3123000071	Eppendorf Research^® plus - 3123000080	Eppendorf Research^® plus - 3124000016	Eppendorf Research^® plus - 3124000024	Eppendorf Research^® plus - 3124000032	Eppendorf Research^® plus - 3124000040	Eppendorf Research^® plus - 3124000059	Eppendorf Research^® plus - 3124000067	Eppendorf Research^® plus - 3124000075	Eppendorf Research^® plus - 3124000083	Eppendorf Research^® plus - 3124000091	Eppendorf Research^® plus - 3124000105	Eppendorf Research^® plus - 3124000113	Eppendorf Research^® plus - 3124000121

ACT label	yes	yes	−	−	−	−	yes	yes	−	−	yes	−	−	yes	yes	−	−	yes	−	−	yes	yes	yes	−	−	−	−	−	−	−	−	−	−	−	−
Product type	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes	Pipettes
Pipetting type	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system	Air-cushion system
Number of channels	1-channel	1-channel	8-channel	12-channel	16-channel	24-channel	1-channel	1-channel	16-channel	24-channel	1-channel	8-channel	12-channel	1-channel	1-channel	8-channel	12-channel	1-channel	8-channel	12-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel	1-channel
Volume range	0.1 – 2.5 µL	0.5 – 10 µL	0.5 – 10 µL	0.5 – 10 µL	1 – 20 µL	1 – 20 µL	2 – 20 µL	2 – 20 µL	5 – 100 µL	5 – 100 µL	10 – 100 µL	10 – 100 µL	10 – 100 µL	20 – 200 µL	30 – 300 µL	30 – 300 µL	30 – 300 µL	100 – 1,000 µL	120 – 1,200 µL	120 – 1,200 µL	0.25 – 2.5 mL	0.5 – 5 mL	1 – 10 mL	10 µL	10 µL	20 µL	20 µL	25 µL	50 µL	100 µL	200 µL	200 µL	250 µL	500 µL	1,000 µL
Color code	dark gray	medium gray	medium gray	medium gray	light pink	light pink	light gray	yellow	light yellow	light yellow	yellow	yellow	yellow	yellow	orange	orange	orange	blue	dark green	dark green	red	violet	turquoise	medium gray	yellow	light gray	yellow	yellow	yellow	yellow	yellow	blue	blue	blue	blue
Volume increment	0.002 µL	0.01 µL	0.01 µL	0.01 µL	0.02 µL	0.02 µL	0.02 µL	0.02 µL	0.1 µL	0.1 µL	0.1 µL	0.1 µL	0.1 µL	0.2 µL	0.2 µL	0.2 µL	0.2 µL	1 µL	1 µL	1 µL	0.002 mL	0.005 mL	0.01 mL	−	−	−	−	−	−	−	−	−	−	−	−
Operating mode	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical	mechanical
Spring-loaded tip cone	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	no	no	no	no	no	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes
Random measurement error¹⁾	0.1 µL: ± 12%; ± 0.012 µL 0.25 µL: ± 6%; ± 0.015 µL 1.25 µL: ± 1.5%; ± 0.01875 µL 2.5 µL: ± 0.7%; ± 0.0175 µL	0.5 µL: ± 5%; ± 0.025 µL 1 µL: ± 1.8%; ± 0.018 µL 5 µL: ± 0.8%; ± 0.04 µL 10 µL: ± 0.4%; ± 0.04 µL	0.5 µL: ± 8%; ± 0.04 µL 1 µL: ± 5%; ± 0.05 µL 5 µL: ± 2%; ± 0.1 µL 10 µL: ± 1%; ± 0.1 µL	0.5 µL: ± 8%; ± 0.04 µL 1 µL: ± 5%; ± 0.05 µL 5 µL: ± 2%; ± 0.1 µL 10 µL: ± 1%; ± 0.1 µL	1 µL: ± 8%; ± 0.08 µL 2 µL: ± 5%; ± 0.1 µL 10 µL: ± 2%; ± 0.2 µL 20 µL: ± 1%; ± 0.2 µL	1 µL: ± 8%; ± 0.08 µL 2 µL: ± 5%; ± 0.1 µL 10 µL: ± 2%; ± 0.2 µL 20 µL: ± 1%; ± 0.2 µL	2 µL: ± 1.5%; ± 0.03 µL 10 µL: ± 0.6%; ± 0.06 µL 20 µL: ± 0.3%; ± 0.06 µL	2 µL: ± 1.5%; ± 0.03 µL 10 µL: ± 0.6%; ± 0.06 µL 20 µL: ± 0.3%; ± 0.06 µL	5 µL: ± 4%; ± 0.2 µL 10 µL: ± 2%; ± 0.2 µL 50 µL: ± 0.8%; ± 0.4 µL 100 µL: ± 0.6%; ± 0.6 µL	5 µL: ± 4%; ± 0.2 µL 10 µL: ± 2%; ± 0.2 µL 50 µL: ± 0.8%; ± 0.4 µL 100 µL: ± 0.6%; ± 0.6 µL	10 µL: ± 1%; ± 0.1 µL 50 µL: ± 0.3%; ± 0.15 µL 100 µL: ± 0.2%; ± 0.2 µL	10 µL: ± 2%; ± 0.2 µL 50 µL: ± 0.8%; ± 0.4 µL 100 µL: ± 0.3%; ± 0.3 µL	10 µL: ± 2%; ± 0.2 µL 50 µL: ± 0.8%; ± 0.4 µL 100 µL: ± 0.3%; ± 0.3 µL	20 µL: ± 0.7%; ± 0.14 µL 100 µL: ± 0.3%; ± 0.3 µL 200 µL: ± 0.2%; ± 0.4 µL	30 µL: ± 0.7%; ± 0.21 µL 150 µL: ± 0.3%; ± 0.45 µL 300 µL: ± 0.2%; ± 0.6 µL	30 µL: ± 1%; ± 0.3 µL 150 µL: ± 0.5%; ± 0.75 µL 300 µL: ± 0.3%; ± 0.9 µL	30 µL: ± 1%; ± 0.3 µL 150 µL: ± 0.5%; ± 0.75 µL 300 µL: ± 0.3%; ± 0.9 µL	100 µL: ± 0.6%; ± 0.6 µL 500 µL: ± 0.2%; ± 1 µL 1000 µL: ± 0.2%; ± 2 µL	120.0 µL: ± 0.9%; ± 1.08 µL 600 µL: ± 0.4%; ± 2.4 µL 1200 µL: ± 0.3%; ± 3.6 µL	120.0 µL: ± 0.9%; ± 1.08 µL 600 µL: ± 0.4%; ± 2.4 µL 1200 µL: ± 0.3%; ± 3.6 µL	250 µL: ± 1.2%; ± 3 µL 1250 µL: ± 0.2%; ± 2.5 µL 2500 µL: ± 0.2%; ± 5 µL	500 µL: ± 0.6%; ± 3 µL 2500 µL: ± 0.25%; ± 6.25 µL 5000 µL: ± 0.15%; ± 7.5 µL	1000 µL: ± 0.6%; ± 6 µL 5000 µL: ± 0.2%; ± 10 µL 10000 µL: ± 0.15%; ± 15 µL	10 µL: ± 0.6%; ± 0.06 µL	10 µL: ± 0.6%; ± 0.06 µL	20 µL: ± 0.3%; ± 0.06 µL	20 µL: ± 0.3%; ± 0.06 µL	25 µL: ± 0.3%; ± 0.075 µL	50 µL: ± 0.3%; ± 0.15 µL	100 µL: ± 0.2%; ± 0.2 µL	200 µL: ± 0.2%; ± 0.4 µL	200 µL: ± 0.2%; ± 0.4 µL	250 µL: ± 0.2%; ± 0.5 µL	500 µL: ± 0.2%; ± 1 µL	1000 µL: ± 0.2%; ± 2 µL
Systematic measurement error¹⁾	0.1 µL: ± 48%; ± 0.048 µL 0.25 µL: ± 12%; ± 0.03 µL 1.25 µL: ± 2.5%; ± 0.031 µL 2.5 µL: ± 1.4%; ± 0.035 µL	0.5 µL: ± 8%; ± 0.04 µL 1 µL: ± 2.5%; ± 0.025 µL 5 µL: ± 1.5%; ± 0.075 µL 10 µL: ± 1%; ± 0.1 µL	0.5 µL: ± 12%; ± 0.06 µL 1 µL: ± 8%; ± 0.08 µL 5 µL: ± 4%; ± 0.2 µL 10 µL: ± 2%; ± 0.2 µL	0.5 µL: ± 12%; ± 0.06 µL 1 µL: ± 8%; ± 0.08 µL 5 µL: ± 4%; ± 0.2 µL 10 µL: ± 2%; ± 0.2 µL	1 µL: ± 12%; ± 0.12 µL 2 µL: ± 8%; ± 0.16 µL 10 µL: ± 4%; ± 0.4 µL 20 µL: ± 2%; ± 0.4 µL	1 µL: ± 12%; ± 0.12 µL 2 µL: ± 8%; ± 0.16 µL 10 µL: ± 4%; ± 0.4 µL 20 µL: ± 2%; ± 0.4 µL	2 µL: ± 5%; ± 0.1 µL 10 µL: ± 1.2%; ± 0.12 µL 20 µL: ± 1%; ± 0.2 µL	2 µL: ± 5%; ± 0.1 µL 10 µL: ± 1.2%; ± 0.12 µL 20 µL: ± 1%; ± 0.2 µL	5 µL: ± 6%; ± 0.3 µL 10 µL: ± 3%; ± 0.3 µL 50 µL: ± 1.2%; ± 0.6 µL 100 µL: ± 1%; ± 1 µL	5 µL: ± 6%; ± 0.3 µL 10 µL: ± 3%; ± 0.3 µL 50 µL: ± 1.2%; ± 0.6 µL 100 µL: ± 1%; ± 1 µL	10 µL: ± 3%; ± 0.3 µL 50 µL: ± 1%; ± 0.5 µL 100 µL: ± 0.8%; ± 0.8 µL	10 µL: ± 3%; ± 0.3 µL 50 µL: ± 1%; ± 0.5 µL 100 µL: ± 0.8%; ± 0.8 µL	10 µL: ± 3%; ± 0.3 µL 50 µL: ± 1%; ± 0.5 µL 100 µL: ± 0.8%; ± 0.8 µL	20 µL: ± 2.5%; ± 0.5 µL 100 µL: ± 1%; ± 1 µL 200 µL: ± 0.6%; ± 1.2 µL	30 µL: ± 2.5%; ± 0.75 µL 150 µL: ± 1%; ± 1.5 µL 300 µL: ± 0.6%; ± 1.8 µL	30 µL: ± 3%; ± 0.9 µL 150 µL: ± 1%; ± 1.5 µL 300 µL: ± 0.6%; ± 1.8 µL	30 µL: ± 3%; ± 0.9 µL 150 µL: ± 1%; ± 1.5 µL 300 µL: ± 0.6%; ± 1.8 µL	100 µL: ± 3%; ± 3 µL 500 µL: ± 1%; ± 5 µL 1000 µL: ± 0.6%; ± 6 µL	120.0 µL: ± 6%; ± 7.2 µL 600 µL: ± 2.7%; ± 16.2 µL 1200 µL: ± 1.2%; ± 14.4 µL	120.0 µL: ± 6%; ± 7.2 µL 600 µL: ± 2.7%; ± 16.2 µL 1200 µL: ± 1.2%; ± 14.4 µL	250 µL: ± 4.8%; ± 12 µL 1250 µL: ± 0.8%; ± 10 µL 2500 µL: ± 0.6%; ± 15 µL	500 µL: ± 2.4%; ± 12 µL 2500 µL: ± 1.2%; ± 30 µL 5000 µL: ± 0.6%; ± 30 µL	1000 µL: ± 3%; ± 30 µL 5000 µL: ± 0.8%; ± 40 µL 10000 µL: ± 0.6%; ± 60 µL	10 µL: ± 1.2%; ± 0.12 µL	10 µL: ± 1.2%; ± 0.12 µL	20 µL: ± 0.8%; ± 0.16 µL	20 µL: ± 1%; ± 0.2 µL	25 µL: ± 1%; ± 0.25 µL	50 µL: ± 0.7%; ± 0.35 µL	100 µL: ± 0.6%; ± 0.6 µL	200 µL: ± 0.6%; ± 1.2 µL	200 µL: ± 0.6%; ± 1.2 µL	250 µL: ± 0.6%; ± 1.5 µL	500 µL: ± 0.6%; ± 3 µL	1000 µL: ± 0.6%; ± 6 µL
Autoclavable	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes
Consumables	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	only epT.I.P.S. 384	only epT.I.P.S. 384	epT.I.P.S.^®	epT.I.P.S.^®	only epT.I.P.S. 384	only epT.I.P.S. 384	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®	epT.I.P.S.^®
Open system (third party consumables)	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes
Connectivity	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–
Delivery content	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x2)	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x3)	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x2), Multi-channel tool	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x3), Multi-channel tool	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x2), Multi-channel tool	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x3), Multi-channel tool	Pipette, epT.I.P.S.^® Box 2.0 pipette tips, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x2), Unlocking tool, Multi-channel tool	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking clip to prevent spring action (x2), Unlocking tool, Multi-channel tool	Pipette, epT.I.P.S.^® pipette tips sample bag, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Protection filter (x10), Pipette wrench	Pipette, epT.I.P.S.^® pipette tips sample bag, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Protection filter (x10), Pipette wrench	Pipette, epT.I.P.S.^® pipette tips sample bag, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Protection filter (x10), Pipette wrench	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action	Pipette, Adjustment tool, Adjustment seal for temporary adjustment (x5), Grease for pipettes, Locking ring to prevent spring action

1)The listed values for 10%, 50%, and 100% of the nominal volume are based on tests complying with DIN EN ISO 8655, Parts 2 or 5. If listed, the smallest adjustable volume provides additional data.

Customer voices: Eppendorf Research^® plus

“The pipettes are easy to handle, precise and ergonomic. Accuracy and reproducibility was excellent. Tested more than 200000 samples using this pipette.”

Suresh Arakera

Karnatak University, India

Write your own review!

Customer voices: Eppendorf Research^® plus

“I've used many different pipettor sets but none match the quality of this product. They are highly ergonomic, accurate, and durable. These are the most coveted pipettors in every lab I've worked in.”

Alberto Gomez

Crown Bioscience, USA

Write your own review!

Customer voices: Eppendorf Research^® plus

“This pipette is great. We rely upon it for everything we do. I love Eppendorf and all their pipettes are great quality.”

Lillian Levin

University of Pennsylvania, USA

Write your own review!

You might also consider

Eppendorf ColorTag pipette accessories, designed for optimal pipette identification and customization

ColorTag pipette marking rings

Flexible silicone marking rings that attach easily to any Eppendorf pipette and many other liquid handling instruments, for customizable labeling.

Eppendorf Research^® 3 neo

Adaptable, ergonomic, and reliable mechanical air-cushion pipette. Shorter operating button, fast volume adjustment, and volume lock.

Eppendorf Reference^® 2

Mechanical air-cushion pipette for outstanding precision and accuracy. Fast and ergonomic single-button operation.

Move It® adjustable multi-channel pipettes from Eppendorf, with electronic and mechanical micropipettes shown

Move It^® Adjustable Tip Spacing Pipettes

Mechanical (Research plus) or electronic (Xplorer plus) adjustable tip spacing multi-channel pipettes for transferring multiple samples between different formats.

epT.I.P.S.^® BioBased

Pipette tips made from 100 % biobased plastic which can be traced back to biological waste material.

epT.I.P.S.^® 384

High-quality and robust 384 micropipette tips

Eppendorf Xplorer® / Xplorer plus single- and multi-channel electronic pipettes

Eppendorf Xplorer^®/ Eppendorf Xplorer^® plus

Electronic air-cushion pipette for a large variety of applications. Intuitively adjustable parameters for easy, fast, and accurate pipetting.

The Multipette® E3x, a digital repeater pipette by Eppendorf

Multipette^® E3/Multipette^® E3x

Electronic multi-dispenser pipette. Like the M4, but with far more options, e.g. for dilution series, titration, automatic dispensing into microplates and vessel series.

Our Pipetting System Finder: Your lab’s matchmaker

Unsure about the right pipetting system for your application? Is it a standard pipette, a multi-dispenser, or perhaps even a pipetting robot?

Find out with our web app and receive recommendations for instrument and suitable consumables.

Try now

You are about to leave this site.

Eppendorf Research® plus

The Eppendorf Research® plus mechanical pipettes are available as 1-, 8-, 12-, 16-, 24-channel and adjustable tip spacing variant Move It®

The Eppendorf Research® plus was the first mechanical pipette to receive the "My Green Lab" ACT label

4-digit volume display on Eppendorf Research® plus mechanical pipettes