Tailoring Oxygen Transfer: A Key Driver for Bioprocess Intensification

In high-density fermentation of aerobic bacteria and fungi, for example, a large amount of oxygen must be introduced into the medium to avoid oxygen limitation during robust microbial growth. In other applications, like the cultivation of microaerophilic bacteria for probiotics production or gut microbiome research, the DO concentration must be controlled precisely at a low level.

In this webinar, we showcase advanced strategies to control the dissolved oxygen concentration in the culture medium and to reproduce it at different scales.

Key Learning Objectives:

• Importance of bioreactors’ oxygen transfer capabilities for bioprocess scale-up
• Method for measuring the oxygen transfer rate (OTR) of a bioreactor
• Hands-on expertise on how to optimize oxygen supply in high-density fermentation processes
• Hands-on expertise on how to establish microaerobic conditions for lactic acid bacteria bioprocesses

Speaker
Ying Yang, Senior Research Scientist, Bioprocess, Eppendorf Inc.'

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