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BioFlo® 610
BioCommand Setup
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Pilot production system without the traditional cost or footprint. This modular system is offered with a comprehensive set of standard off-the-shelf options for rapid initial delivery, as well as easy customization at any time, should your process needs change. The entire system is built-on a mobile skid that fits through virtually any doorway, making it easy to move and share between labs in research, pilot plant and GMP environments.
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The BioFlo 610 is a compact, mobile, pilot-plant fermentor for process development and small-scale production. A modular design and wide variety of standard and optional components provide the flexibility to customize the system to meet your process requirements.
Working volumes
• 16.0 L to 50.0 L
• 32.0 L to 100.0 L
Gas flow control
• Single gas
• Two gas
• Overlay (valve only)
Gas flow
• 1 TMFC, 50 L vessels, 2.0 – 75 SLPM
• 1 TMFC, 100 L vessels, 3.0 – 150 SLPM
• 2 TMFC, 50 L vessels, 2.0 – 75/0.6 - 32 SLPM
• 2 TMFC, 100 L vessels, 3.0 – 150/1.0 - 64 SLPM
Exhaust line
• Exhaust condenser
• Automatic pressure control
Impellers
• Rushton-type, standard
• Pitched-blade, optional
• Marine, optional
Sensors
• Single or redundant pH/DO
• Redox
• Foam/level
Addition and sampling
• Resterilizable sampling valve
• Resterilizable addition valves (4 max)
• 1.5 in sanitary fitting 7-port septum
• Addition vessels (glass/stainless steel)
• Sterile sampling assembly
Documentation packages to support qualification in GMP regulated processes
• Basic Package
• Basic Plus Package
• Enhanced Package
Utility regulator and pre-filter kits
• Process air pre-filter/regulator kit
• Instrument air pre-filter/regulator kit
• Water pre-filter/regulator kit
• Process steam regulator kit
• Utility steam pre-filter/regulator kit
• Utility connection kit
Additional options
• Sprayballs for clean-in-place of vessel
• External variable-speed pumps
• External scales
• Spare parts kits
• Preventive maintenance kits
• System passivation
• Low pressure seal alarm for double mechanical seal
• Glycol/chiller heat exchanger
Working volumes
• 16.0 L to 50.0 L
• 32.0 L to 100.0 L
Gas flow control
• Single gas
• Two gas
• Overlay (valve only)
Gas flow
• 1 TMFC, 50 L vessels, 2.0 – 75 SLPM
• 1 TMFC, 100 L vessels, 3.0 – 150 SLPM
• 2 TMFC, 50 L vessels, 2.0 – 75/0.6 - 32 SLPM
• 2 TMFC, 100 L vessels, 3.0 – 150/1.0 - 64 SLPM
Exhaust line
• Exhaust condenser
• Automatic pressure control
Impellers
• Rushton-type, standard
• Pitched-blade, optional
• Marine, optional
Sensors
• Single or redundant pH/DO
• Redox
• Foam/level
Addition and sampling
• Resterilizable sampling valve
• Resterilizable addition valves (4 max)
• 1.5 in sanitary fitting 7-port septum
• Addition vessels (glass/stainless steel)
• Sterile sampling assembly
Documentation packages to support qualification in GMP regulated processes
• Basic Package
• Basic Plus Package
• Enhanced Package
Utility regulator and pre-filter kits
• Process air pre-filter/regulator kit
• Instrument air pre-filter/regulator kit
• Water pre-filter/regulator kit
• Process steam regulator kit
• Utility steam pre-filter/regulator kit
• Utility connection kit
Additional options
• Sprayballs for clean-in-place of vessel
• External variable-speed pumps
• External scales
• Spare parts kits
• Preventive maintenance kits
• System passivation
• Low pressure seal alarm for double mechanical seal
• Glycol/chiller heat exchanger
- Pilot-scale fermentation of aerobic and anaerobic bacteria, yeasts, and fungi
- Suitable for batch, fed-batch, and continuous processes
- RPC (Reactor Process Control) software
- 50 L and 100 L 316L stainless-steel electropolished vessels with 3:1 aspect ratios
- Integrated load cell
- 3-Fixed speed peristaltic pumps for the additions, harvest and pH control
- Mobile design
- Includes rushton-type impellers as standard with pitched-blade and marine blade as optional
- Industrial touchscreen interface