text.skipToContent text.skipToNavigation
No results found
Search Suggestions

Mastercycler® nexus - PCR Thermal Cycler

Product Information

The versatile Mastercycler® nexus enables you to select the PCR consumables that best fit your assay. The nexus PCR cycler can accommodate 96-well PCR plates, 0.2 mL PCR tubes, 0.2 mL PCR tube strips, and 0.5 mL PCR tubes. With less than 40 dB[a] noise emission, the nexus is whisper quiet, while also being energy efficient.

You will find additional download material at the bottom of this page

Products (4)

Services (21)

Accessories (5)

VisioNize (1)

    • 230 V/50 – 60 Hz (EU), aluminum block, 96 × 0.2 mL PCR tubes, 1 PCR plate (96 wells) or up to 38 × 0.5 mL Eppendorf PCR tubes
    More Product Details ...
    Catalog no. 6331000017
    € 9,104.00

      • 230 V/50 – 60 Hz (EU), aluminum block, 96 × 0.2 mL PCR tubes, 1 PCR plate (96 wells) or up to 38 × 0.5 mL Eppendorf PCR tubes
      More Product Details ...
      Catalog no. 6333000014
      € 7,606.00

        • 230 V/50 – 60 Hz (EU), aluminum block, 96 × 0.2 mL PCR tubes, 1 PCR plate (96 wells) or up to 38 × 0.5 mL Eppendorf PCR tubes
        More Product Details ...
        Catalog no. 6332000010
        € 5,872.00

          • 230 V/50 – 60 Hz (EU), aluminum block, 96 × 0.2 mL PCR tubes, 1 PCR plate (96 wells) or up to 38 × 0.5 mL Eppendorf PCR tubes
          More Product Details ...
          Catalog no. 6334000018
          € 7,406.00

          Product Information

          Technical Data



          The Mastercycler® nexus PCR cycler provides you with flexibility in many forms. Conduct PCR runs with a range of standard vessel types, from 0.2 mL tubes to 96 well plates using a single 96-well aluminum block. So there is no need to buy additional blocks, and for even faster ramp rates, silver block variants can be used instead.

          If you need higher throughput, simply connect up to two eco cyclers to a programmable nexus thermal cycler for additional capacity. The configuration can also include the nexus X2 eco units – providing up to 6 independently operating blocks. The Mastercycler nexus cycler can even email you when the PCR run is complete – what else do you need from a PCR cycler?

          The flexlid® concept for effortless height adjustment

          The flexlid enables the nexus to easily deal with all types of PCR consumables, from low volume wells all the way up to 0.5 mL PCR tubes, and of course all common PCR plates.  

          Gradient with SteadySlope® technology

          To ensure that heating and cooling ramp rates are exactly the same in both gradient and normal operation, the Mastercycler nexus gradient option features SteadySlope technology. This gives you identical temperature control characteristics in both optimization and routine experiments.

          Certified quality

          All Eppendorf cyclers follow these quality guidelines:
          • Individual quality control certificates
          • Calibration according to national and international standards, e.g. NIST (USA), DKD/PTB (Germany), UKAS/NPL (UK)
          • UL/cUL listed

          Concerned about your lab's carbon footprint or electricity bill?

          Eppendorf's Mastercycler nexus is optimized for low power consumption – regardless of whether the cycler is running, idle, or in standby mode.

          Suffering from noise in the lab?

          With many different instruments in the lab, noise levels can easily become too high. The Mastercycler nexus is a whisper quiet PCR cycler. Low noise levels make working in your lab more pleasant and enjoyable – particularly when you’re thinking about how to achieve your next big breakthrough!

          Improving ergonomics across the lab

          Ergonomics goes far beyond just the ergonomically designed chair. At Eppendorf, we began optimizing our laboratory devices for ergonomics in the early 1970s.

          In 2003, we launched the PhysioCare Concept®, focusing on ergonomic liquid handling devices, like our pipettes.

          Since then we’ve broadened the Eppendorf PhysioCare concept to include many laboratory products, including PCR cyclers. Our aim is to offer a holistic solution for harmonizing the workflow in your laboratory with your health and wellbeing.

          For the Eppendorf Mastercyler range, this means:

          • Ergonomically designed lid closure
          • Low noise level for convenient working conditions at the bench
          • Small footprint to enable position in direct arm reach at your bench
          • Standardized user-interface concept for intuitive handling of devices
          • Guided software for easy handling

          Further information about the Eppendorf PhysioCare concept:


          Simple, intuitive documentation and tracking

          The eLABJournal® Electronic Lab Notebook offers an intuitive and flexible way to document research and track research data, including optimal PCR cycler temperatures and results. Improve efficiency when documenting, organizing, searching, and archiving collected data. With the free eLABJournal add-ons, you can extend the functionality of eLABJournal to a fully integrated Laboratory Information Management System.

          Start a free 30-day trial!

          Visit www.eLABJournal.com

          Efficient lab and device management with VisioNize® Lab Suite

          Are you interested in monitoring your lab devices and receiving notifications e.g., for device alarms? A digital, connected lab offers even more.

          Gain access to a modular range of digital services and choose what works for your lab. VisioNize Lab Suite offers everything you need as a Lab Manager or Scientist to get started to digitally manage your lab for increased sample security, compliance needs and maintenance management.

          Chart your own course to digital lab excellence! Find out more

          Disposal of packaging

          The packaging of the PCR cycler contains different materials, this includes cardboard, a plastic dust cover, and some foam parts. Recycling of materials becomes more and more important every day: Are you aware that nearly all cardboard material is recycled in Europe? Our cycler packaging cardboard material consists of approx. 60 % recycling material. Please support the global sustainability initiative of recycling valuable raw material by also collecting the cycler cardboard packaging material and disposing of it in the appropriate collection container at your organization. In respect to the plastic dust cover made of LD-PE and the foam parts, we recommend to select a dedicated recycling partner where PE material can be recycled. We suggest you contact your local waste hauler or facility management team to understand the available recycling options for your organization.

          Disposal of instrument

          Our cyclers last for many years, but if they need to be replaced, we kindly ask you to fulfill local requirements for disposal of these instruments. We strongly recommend a certified local recycling partner with experience in instruments with electronics. Keeping it "local" reduces the impact of transportation, and the "certified" aspect is recommended due to the safe and sustainable removal of specific parts.


          This piece of equipment was used in a laboratory and/or was used to handle biological samples. Please keep in mind to adequately decontaminate the equipment which needs to be disposed. Check local requirements. For more information, get in contact with your local biosafety officer and/or waste officer. Check if your local recycling partner has special instructions and/or documentation requirements. You may also use the Eppendorf decontamination form sheet as guidance.