DASGIP® Parallel Bioreactor System
DASGIP Parallel Bioreactor System for Microbiology Bioblock
DASGIP Bioblock, BioBLU 1c with medium
DASware control 5 lab, woman at PC
Product Information
Eppendorf DASGIP Parallel Bioreactor Systems are designed to deliver optimal bioprocess performance in benchtop configurations. Scalable monitoring and control functionality enable users to achieve valid and reproducible results in an economical manner. Their modular design addresses the unique requirements of various applications in both cell culture and microbiology.You will find additional download material at the bottom of this page
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Product Information
Technical Data
Applications
Features
DASGIP Parallel Bioreactor Systems for R&D and process development in both cell culture and microbiology allow for advanced bioprocess control and automation. Parallel processing, precise control of all relevant parameters, user-defined profiles, and innumerable automation features result in accelerated and highly efficient process development. Our DASware software solutions support Design of Experiments (DoE), process historians and comprehensive data management. Configurable solutions address the unique requirements of microbial, mammalian and human cells, stem cell applications, as well as biofuel and biopolymer processes.
| Specifications | DASGIP® System for Cell Culture | DASGIP® System for Microbiology |
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| Application | Cell culture | Microbiology |
| Number of parallel units | Up to 16 | Up to 16 |
| Software | DASware control, other DASware optional | DASware control, other DASware optional |
| User Interface | Process computer with monitor | Process computer with monitor |
| Typical power consumption (4-fold system without process computer) |
480 W (at 230 V)/ 432 W (at 115 V) (595 W/552 W without DASGIP Bioblock) |
541 W (at 230 V)/ 467 W (at 115 V) (639 W/584 W without DASGIP Bioblock) |
| Dimensions (W × D × H, 4-fold system without process computer) | 140 x 70 x 53 cm (55 x 28 x 21 in) | 140 x 70 x 53 cm (55 x 28 x 21 in) |
| Typical weight |
78 kg (60 kg without DASGIP Bioblock) |
96 kg (78 kg without DASGIP Bioblock) |
| Bacteria/Yeast/Fungi | yes | yes |
| Mammalian/Animal | yes | yes |
| Insect | yes | yes |
| Interchangeable Vessels | yes | yes |
| Validatable | no | no |
| Stem cells | yes | yes |
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Bioreactors |
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| Vessels | Glass/single-use vessels | Glass/single-use vessels |
| Sterilization |
Autoclavable/ pre-sterilized |
Autoclavable/ pre-sterilized |
| Total volume | 1.5 L to 2.3 L | 1.3 L to 2.1 L |
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Agitation |
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| Drive | Direct/magnetic overhead drive | Direct/magnetic overhead drive |
| Speed ranges |
30 – 1,250 rpm (standard)/ 100 – 1,600 rpm (optional) |
100 – 1,600 rpm (standard)/ 30 – 1,250 rpm (optional) |
| Impellers | Pitched-blade | Rushton-type |
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Gassing |
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| Gas supply | TMFC; overlay and/or sparger | TMFC/Rotameter; sparger |
| Standard gas flow rates | 0.1 – 50 sL/h, 0.1 – 40 sL/h CO2 (DASGIP MX4/4, other modules available) | 0.5 – 250 sL/h, 0.5 – 150 sL/h CO2 (DASGIP MX4/4H, other modules available) |
| Standard gas mixing | Air, N2, O2 and/or CO2 | Air, N2, O2 and/or CO2 |
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Feeding |
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| Feed lines per vessel | Up to 8 | Up to 8 |
| Standard feed rates (depending on tube diameter) |
0.3 – 9.5 mL/h to 13 – 420 mL/h (DASGIP MP8) 10 – 70 mL/h to 0.4 – 5 L/h (DASGIP MP4) |
0.3 – 9.5 mL/h to 13 – 420 mL/h (DASGIP MP8) 10 – 70 mL/h to 0.4 – 5 L/h (DASGIP MP4) |
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Monitoring and Control |
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| Temperature control | Heating and cooling integrated in DASGIP Bioblock (additional cooling fingers optional) | Heating and cooling integrated in DASGIP Bioblock (additional cooling fingers optional) |
| Standard temperature range (at 25° C room temp.) | 5 K above cooling agent temperature – 99°C (DASGIP Bioblock)1) | 5 K above cooling agent temperature – 99°C (DASGIP Bioblock)1) |
| pH control | − | Acid and/or base, and other set-ups |
| DO control | Cascade (O2 concentration, gas flow rate), and other set-ups | Cascade (agitation speed, optional O2 concentration, optional gas flow rate), and other set-ups |
| ORP (redox) measurement | - | Optional |
| Level/foam | Optional | Optional |
| OD measurement |
Optional (DASGIP OD4) |
Optional (DASGIP OD4) |
| Exhaust condensation | Water-cooled or liquid-free (Peltier with DASGIP EGC4) | Water-cooled or liquid-free (Peltier with DASGIP EGC4) |
| Exhaust analysis |
Optional (DASGIP GA4) |
Optional (DASGIP GA4) |
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1)Application-specific operating conditions apply. |
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- Research and development in cell culture and microbiology
- Lab scale fermentation of aerobic and anaerobic bacteria, yeasts and fungi
- Cultivation of mammalian, insect and human cell lines
- Special applications such as stem cell culture or biofuel/biopolymer development
- Parallel operation of up to 16 glass or single-use bioreactors
- DASGIP Bioblock for advanced and user-friendly temperature control
- Suitable for cell culture and microbial fermentation
- Modular design of control units allows for flexible system configurations that meet the demands of specific applications
- Control of agitation, pH, level, and DO (including customizable cascade modes) in each bioreactor
- Variable speed pumps for accurate liquid addition and operation in batch, fed-batch, continuous, and cyclic perfusion mode
- Optical absorbance measurement for online calculation of e.g. OD600 or cell dry weight
- TMFC individual gas mixing of air, N2, O2 and CO2
- Online calculation of OTR, CTR and RQ
- DASware control software for advanced process control
- Compatible with DASware Software Suite for interconnectivity and bioprocess information management
