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Bioprocessing in Vaccine Development

At Eppendorf, our aim is to empower your upstream bioprocessing in vaccine development. We provide tools that help you accelerate process development by parallel bioprocessing, increasing turn-around, and leveraging the full potential of bioprocess data. We support you in increasing cost-efficiency by intensifying bioprocesses and streamlining scale-up. You discover new ways for vaccine production. We deliver solutions to help bringing your bioprocess to the next level. So come and talk to us, we’re all ears.

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Supporting you in your pursuit of efficiency

Speed up bioprocess development

We offer orchestrated bioreactor, software, and service solutions that let you combine experimental efficiency with smart use of data. Discover our bioprocess solutions that support you to increase speed through parallel processing, automation, and efficient data analysis. Find out how our software ecosystem can leverage the power of artificial intelligence to reduce the experimental workload in process development.

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Discover our bioprocess development solutions

Scale-up to clinical and commercial manufacturing

Bioprocess insight gained at small-scale can help to ensure a high level of success in your large-scale processes. Our scalable bioprocess solutions help you seamlessly translate your R&D successes into manufacturing. Our solution package of bioprocess controllers, bioreactors, bioprocess SCADA software, and services support the compliance of your bioprocesses with GMP requirements in clinical and commercial manufacturing.

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Discover our clinical and commercial manufacturing solutions

Intensify your bioprocess

We support you in increasing process productivity and lowering production costs. Our bioprocess controllers and software support the use of Process Analytic Technology (PAT) to fine-tune process control for improved reproducibility and quality. Our bioreactor systems let you choose between batch, fed-batch, and perfusion cultures to help optimize yield and productivity.

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Discover our bioreactor systems

Reduce risks and save time with single-use technology

Our single-use technology helps you increase throughput, flexibility, and safety in bioprocessing. BioBLU^® Single-Use Bioreactors eliminate the need for labor-intensive cleaning procedures, cleaning validation, and hold time validation. With built-in measures to minimize the risk of contamination, they enable you to act quickly while significantly reducing the risk of costly and time-consuming batch failures in both research and manufacturing environments.

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Discover BioBLU Single-Use Bioreactors

Get to know the Eppendorf bioprocess products

The Eppendorf bioprocess portfolio offers scalable bioprocess systems, single-use bioreactors, software solutions, and services to efficiently develop processes and move them from R&D to manufacturing.

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Bioprocess development for various vaccine types

Bioreactor systems for bioprocess development for viral vector production

Viruses

Discover how our solutions can help you with your process development for viral vector production.

Bacteria

Discover how we can work together to take your production of whole pathogens, proteins, or plasmids through bacterial fermentation to new heights.

Recombinant proteins made in cells

We aim to help you bring your cell culture bioprocess to the next level. Find out more!

Get inspired by these resources on vaccine production in bioreactors

Webinar: Vero cell cultivation for vaccine production

Anchorage-dependent cells, such as Vero cells, are widely used as a platform for viral vector production. Their cultivation in stirred-tank bioreactors requires a growth matrix. Learn about the setup of perfusion bioprocesses for the cultivation of Vero cells grown on microcarriers and Fibra-Cel^® Disks.

Webinar: Stirred tank bioreactors in vaccine development

The use of cell culture in bioreactors offers a standardized, scalable, and cost-effective procedure for developing vaccines. Learn, how suspension cells were efficiently cultivated in bioreactors to produce AAV particles and COVID-19 spike proteins in suspension culture.

Vaccine research discovered

Find out how the Eppendorf solutions support your vaccine discovery workflow from molecular biology, to cell cultivation, to sample storage.

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Ebook: Bioprocessing solutions for vaccine development

Discover workflows and technologies that could accelerate your vaccine research. This ebook provides you with application notes, product guides, and expert insights to support your vaccine research and development.

Ebook: Facing the challenges in vaccine upstream bioprocessing

Vaccine manufacturers are facing the challenge of developing new products to serve unmet needs and fulfill the demands in an economically viable way. Read expert views and case studies on some of the hot topics in vaccine bioprocess development.

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Infographic: Vaccine development workflow

The vaccine development journey involves several stages, from selecting lead candidates to process development, and manufacturing. Gain a better understanding of the vaccine development workflow, and learn about the problems and potential solutions of each stage.

How our customers use our products

Vaxcyte^®: Scaling up cell-free expression

Read, how scientists at the University of Maryland School of Medicine and Vaxcyte^® , Inc. scaled-up the cell-free expression of a vaccine candidate in Eppendorf bioreactor systems.

Download case study

Hunan Cancer Hospital: Perfusion cultivation of Vero cells

Read, how researchers at the Hunan Cancer Hospital, the Hunan Clinical Medical Research Center of Gastrointestinal Tumor, and Hefei University set up perfusion cultivation of Vero cells on microcarriers using the BioFlo^® 320 bioreactor control system equipped with Cell-Lift impeller and decanter column.

Download application note

Worcester Polytechnic Institute: Vero cell culture on Fibra-Cel^® Disks

Scientists at the Worcester Polytechnic Institute found bioreactors with a packed-bed made of Fibra-Cel^® Disks to be an excellent choice for culturing Vero cells.

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Bioprocessing in Vaccine Development