CellXpert^® C170i - Cell Culture Incubator

Easy cleaning, reliable contamination prevention

Prevention of lab downtime and sample loss is essential for you to deliver cell culture results in time? You cannot afford to spend too much time and money on standardized cleaning of your cell culture incubator, documentation or on changing costly, non-sterilizable, fan-associated HEPA filters?

Contamination prevention with CellXpert^® CO₂ incubators follows a simple concept: If it's easy to do, it's more likely to get done.

• 180 °C high temperature disinfection with illustrated step-by-step instructions on screen and downloadable performance protocol for standardized procedures
• Minimal internal incubator parts removed in 40 s and wiped quickly
• Nowhere to hide for contaminants and cleaned fast: Smooth, seamless incubator chamber
• Fanless design
• No non-sterilizable fan-associated HEPA filters that can become potential contamination sources
• Options for copper and segmented inner doors for additional protection

Learn more: Video – Easy cleaning and reliable contamination prevention with CellXpert CO2 incubators

Fanless incubator design = No costly, fan-associated internal HEPA filters

One of the strongest contamination protectors in the CellXpert is the fanless design. It effectively reduces the spread of airborne contaminants and therefore eliminates the need for fan-associated internal HEPA filters.

Generally, HEPA filter cartridges are heat-sensitive and need to be removed before starting an HTD. For reinstallation of the HEPA filter (that traps particles, but does not destroy them), extended door opening and reaching inside the clean chamber a full arm´s length is necessary. These factors pose a high risk of introducing new contaminants into the incubator.

The CellXpert cell culture incubator reduces significant recurring costs for fan-associated HEPA filters that must be replaced regularly – while offering strong contamination protection.

Do you need a fan for fast atmosphere recovery after door opening and spatial homogeneity?

Fanless cell culture incubators have always been a solid choice for customers with a high demand for easy cleaning, effective contamination prevention, and protection from vibrations and air turbulences. Also, the reduced number of internal parts compared to fan-assisted cell culture incubators (e.g. ducts, filters, fan itself etc.) is advantageous regarding optimal use of space inside. In the past, however, fast atmosphere recovery after door opening and spatial homogeneity compared to fan-assisted cell culture incubators have always been a challenge.

The new CellXpert^® solves this former disadvantage by implementing various technologies: multiple, independent temperature sensors (see section below), as well as advanced microprocessor and gas control.

The result: The CellXpert^® cell culture incubators can easily compete with fan-assisted devices regarding recovery and spatial homogeneity of CO₂ and temperature (see below).

Optimized cell growth conditions for reproducible results

You cannot afford to spend time, money, or valuable source material on additional experiments due to insufficient reproducibility? You can reduce time-to-market or time-to-publication with CellXpert^® cell culture incubators by standardized procedures and:

• Precise temperature uniformity throughout the incubator chamber, verified at 27 spots inside based on German Norm DIN 12880
• Fast gas and temperature recovery < 5 min without setpoint overshoot
• Protection from vibrations and turbulence with fanless incubator design, so cell culture vessels can also be located on the top shelf
• State-of-the-art dual channel IR-sensor for CO₂ control and platinum-coated ZrO₂ sensor for variants with O₂ control (both sensors are high temperature resistant)
• Dedicated IQ/OQ and Eppendorf service contracts

Multiple temperature sensors at various locations inside the incubator

To accurately compare cell growth in vessels at different locations inside the incubator, the temperature needs to be highly uniform. Together with advanced microprocessor control, this is achieved in CellXpert^® cell culture incubators by replacing the traditional configuration of one or two temperature sensors (the second almost always just used to control for overtemperature) with multiple, independent sensors in different locations. The effectivity of this novel approach has been verified by measuring the temperature deviation among 27  spots inside the incubator based on the German Norm DIN 12880 – and far exceeding the requisite specification.

Does it matter where you put the vessels inside your cell culture incubator?
Learn more: White Paper about CO₂ incubator homogeneity

Do you cultivate cells on the top shelf of your fan-assisted cell culture incubator?

Afraid of vibrations or increased medium evaporation?

Have you ever experienced variations between cells grown in vessels on different shelves of your cell culture incubator, especially between the top shelf and others?

These differences can be caused by air turbulences that disrupt the protective micro-atmosphere above the medium. Air turbulence can be generated by fans used to circulate the atmosphere inside standard CO₂ incubators. Additionally, uneven cell growth can occur because the fan may cause the vessels to vibrate – especially in the case of sensitive cells. These effects can be avoided with fanless CO₂ incubators like the CellXpert. Air circulation via convection provides uniform temperatures, fast recovery, and conditions without the risks due to a fan. Enjoy peace of mind using the top shelf and use more valuable space.