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BioFlo® 510

Product Information

SIP benchtop reactors designed to meet the needs of R&D through production.

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epServices (6)


  • BioFlo®/CelliGen® 510
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Catalog no. 0082140294

  • Installation Qualification/Operational Qualification, BioFlo®/CelliGen® 510
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Catalog no. 0082140299

  • BioFlo®/CelliGen® 510
More Product Details ...
Catalog no. 0082140293

  • BioFlo®/CelliGen® 510
More Product Details ...
Catalog no. 0082140295

  • Installation Qualification, BioFlo®/CelliGen® 510
More Product Details ...
Catalog no. 0082140297

  • Operational Qualification, BioFlo®/CelliGen® 510
More Product Details ...
Catalog no. 0082140298

Product Information

Applications

Features

The BioFlo 510 is a compact sterilizable-in-place fermentation system ideal for pilot to small scale production processes. The modular design features a wide variety of standard options allowing this system to be flexible enough to meet most process requirements.
Gas flow
• Various combinations of one, two, three or four TMFCs:
0.06  –   3 SLPM
0.3  –   15 SLPM
0.6  –   32 SLPM
1  –   64 SLPM
• Overlay (valve only)

Exhaust line
• Exhaust condenser
• Manual or automatic pressure control

Impellers
• Rushton-type – Used commonly for robust cell lines such as bacteria, yeasts, and algae, where maximum OTR is desired. Provided as standard on BioFlo 510 fermentors
• Pitched-blade – Commonly used with mammalian, insect or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial and radial mixing.
• Marine – Commonly used with mammalian, insect, or other shear sensitive cell lines for batch, fed-batch or continuous cultures. Produces axial mixing

Sensors
• Single or redundant pH/DO
• Redox
• Foam/level

Addition and sampling
• Resterilizable sampling valve
• Resterilizable addition valves (4 max)
• Resterilizable addition/harvest valve with dip tube (2 max)
• 1.5 in sanitary fitting 7-port septum
• Addition vessels (glass/stainless steel)
• Sterile sampling assembly

Validation
• Basic Package
• Basic Plus Package
• Enhanced Package

Utility regulator & pre-filter kits
• Process air pre-filter/regulator kit
• Instrument air pre-filter/regulator kit
• Water pre-filter/regulator kit
• Process steam regulator kit
• Utility steam pre-filter/regulator kit
• Utility connection kit

Additional options
• Sprayballs for clean-in-place of vessel
• External variable-speed pumps
• External scales
• Spare parts kits
• Preventive maintenance kits
• Mobile table
• System passivation
• Glycol/chiller heat exchanger