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Cell and Gene Therapy Development

The emerging field of cell and gene therapies (CGT) is a transformative new category of medicine seeking to treat diseases by restoring or reconditioning cells or genes. While both approaches aim to repair the underlying cause of genetic or acquired diseases, cell and gene therapies are distinct from one another in their mechanism of action. Although the fields of cell and gene therapies are in their infancy with regards to clinical applications, the research and development of novel cell and gene therapies is rapidly expanding. Today, more and more CGT applications are making it through R&D towards clinical trials and beyond. Research and development in these application areas require large numbers of high-quality cells. Stirred-tank bioreactors facilitate efficient cell expansion when conventional 2D-culture systems reach their limits.

From a scientific concept to the development of novel therapies

The Eppendorf Bioprocess Unit builds on decades of experience in upstream bioprocessing; for more than ten years Eppendorf is committed to contribute to the advancement of stem cell cultivation in stirred-tank bioreactors. The scalability, robustness, quality, and cost-effectiveness of cell culture processes are key to success when translating basic research to the development of commercially viable cell and gene therapies. Eppendorf supports you in developing powerful upstream bioprocesses for cell and gene therapy development. Contact us to learn more about how we can support you!

Find more information about cell and gene therapy‌

Scale up efficiently

Producing large amounts of cells in conventional 2D-culture systems is very labor- and time-intensive. Stirred-tank bioreactors reduce manual labor when handling large cultures, simplify scale-up, and like this facilitate efficient cell expansion. Eppendorf supports you with transferring your process from flasks or bags to bioreactors and seamlessly scaling-up from small to larger working volumes.

Shorten time to market

Accelerating the development of bioprocesses is key to shorten the time to market. Parallel bioprocess control systems from Eppendorf facilitate parallel experimentation in small working volumes and, like this, process development in a time- and resource-saving manner.

Reproduce culture results

Reproducing culture success requires reproducing the cells’ growth environment. Stirred-tank bioreactors and bioprocess control software from Eppendorf enable you to precisely monitor and control the cells’ growth environment. Like this, you are always well informed on what is happening in your bioreactor and are able to optimize your bioprocess, compare different runs, and reproduce culture results.

Free up scientists’ times

The automation of routine tasks provides scientists more time for valuable research. Bioprocess control software from Eppendorf enables you to automate culture feeding and parameter control to reduce the working time spent on a running process.

Upstream bioprocessing for various cell and gene therapy applications

Optimizing the upstream bioprocess is an essential part of cell and gene therapy development. Stirred-tank bioreactors from Eppendorf provide extensive options for monitoring and control of critical process parameters in real-time. Through scalable bioreactor design, results yielded in small scale can be transferred to larger working volumes.

How our customers use our products

Join the stem cell community

Organized for the first time in 2017, the Stem Cell Community Day (SCCD) connects researchers from academia and industry across the world, to discuss recent advances and new technologies in the field of stem cell production. With a special focus on the controlled cultivation of stem cells in stirred-tank bioreactors, the SCCD is an optimal place to exchange knowledge and share expertise with scientists around the world.
Eppendorf Stem Cell Community Day