This article appeared first in BioNews, Eppendorf’s biannual customer magazine since 1993.
Future proof equipment for changing requirements
“A big advantage of the new controller is the sophisticated modularity of the vessel sizes that ensure an easy exchange of various bioreactor volumes without the need to invest in completely new control systems.” (SenseUp GmbH, Germany, Dr. Regina Mahr)
The current pandemic demonstrates how important it is to adapt rapidly and efficiently to new situations. Missing flexibility and limited workspace are bottlenecks in the transition of a laboratory due to changing projects. Changing the focus of a laboratory results in a long list of problems. Existing bioreactor control systems might require a new hardware configuration or in the worst case need to be exchanged completely, just because they cannot handle the new demands. Designed to fit for now, and in the future, SciVario twin comes with hardware and software features that enable the system to adapt to changing processes.
The flexibility of the system can be found in every single aspect. Scaling up a process, for example, requires advanced thermal mass flow controllers (TMFCs) to ensure reliable and precise gas supply also at larger scales. Current TMFCs are optimized for either small, or larger volumes. Equipped with 14 of our in-house developed improved TMFCs, with a turndown ratio of 12,000:1, the SciVario twin bioprocess controller can be used for both, for small- and bench-scale bioreactors with a size of 0.2 L to 3.7 L without the need of any hardware modifications. Within the near future, the vessel range will be extended to working volumes up to 40 L in single use bioreactors for cell culture applications.
A controller, full of innovations
SciVario twin was developed to control two single use or glass bioreactors individually, or in parallel, in a range of 0.2 L to 40 L. It sets new standards in terms of flexibility, precision, and range. This flexibility is made possible by the advanced hardware of the base unit. In addition to the built-in TMFCs, the innovative bay-drawer concept offers the freedom to flexibly change hardware features, such as additional pumps or sensors.
With thousands of possible drawer combinations and 19 vessel variants at launch, the SciVario twin offers unrivaled flexibility for current and future processes.