What does the term 2DMix-Control technology describe/stand for?

2DMix-Control technology stands for an orbital circular paths with a diameter of 3 mm and up to 3,000 rpm. 2DMix-Control technology generates excellent mixing performance, even for challenging samples. Detaild information can be found in the brochure "Ther value of Mixing".

What is the time setting increments for the ThermoMixer C and ThermoStat C?

Step times of 5 s to 99:30 h or unlimited. Step time range: Stepsize [or increment] 5 s - 1 min: 5 s 1 min - 20 min: 15 s 20 min - 1:00 h: 1 min 1:00 h - 10:00 h: 5 min 10:00 h - 99:30 h: 30 min Further information can be found in the operating manual.

The ThermoMixer C or ThermoMixer F starts to mix and count down before the set temperature is reached. How can that be changed, so that the ThermoMixer C or ThermoMixer F waits until the temperature is reached?

This can be changed in the menu of the device. The device must be changed to "Temp. control" mode than the mixer first starts to mix when the set temperature has been reached. Further information can be found in the operating manual.

Why is it recommended to reduce the speed to 1,000 rpm when using DWPs at temperatures of ≥80°C in the SmartBlock plates (5363 000.039) with the ThermoMixer C and ThermoMixer FP?

Polypropylene DWPs deform at temperatures ≥ 80°C. Deformed plates may become detached from the thermoblock or are more difficult to remove. If you are heating DWPs ≥ 80°C, do not exceed the mixing frequency of 1,000 rpm.

How to perform the cleaning and disinfection of MixMate, ThermoMixer F, ThermoMixer C, ThermoStat C, SmartBlocks, SmartExtender and ThermoTop?

Switch off the device, disconnect the mains/power plug and make sure that no liquid can get into the inside of the housing. When cleaning has been completed, the device should only be connected when it is fully dry on the inside and on the outside. Use lint-free cloth and soft bottle brush or cotton swabs for SmartBlocks and SmartExtender. Do not use any aggressive chemicals on the device or its accessories such as strong and weak bases, strong acids, acetone, formaldehyde, halogenated hydrocarbons or phenol. If the device is contaminated with aggressive chemicals, clean it immediately using a mild cleaning agent and wipe it off with dist. water afterwards. Recommended cleaning agents: mild, soap-based lab cleaner dist. water Recommended disinfectants: ethanol (70%) isopropanol (70%) Please follow the detailed safety instructions in the Operating Manual..

Can cell culture plates be used in the SmartBlock plates?

Cell culture plates comply with the SBS standard can be used in the SmartBlock plates. Temper polystyrene plates up to 70°C max. Further information can be found in the operating manual.

Is it possible to run more than one program in automatic succession on a ThermoMixer or ThermoStat C?

No. Each program has to be chosen and run separately. But the 4 possible steps within a program run in automatic succession.

Can PCR plates be used in SmartBlock plates respectively ThermoMixer FP?

SmartBlock plates and ThermoMixer FP (with the fixed SmartBlock plates) are dedicated for using MTP’s, DWP’s and also other skirted plates which meet the SBS standard. For optimal usage of PCR plates the SmartBlock PCR 96 and PCR 384 in combination with ThermoMixer C or ThermoStat C is the proper choice. These SmartBlocks possess conical bores which surround the conical wells of PCR plates properly for a perfect temperature transition.

Is it possible to use the Eppendorf ThermoMixer C, ThermoMixer F and ThermoStat C permanent?

Yes, this is possible. The customer has just to set the time to endless. But ice may form on the thermoblock if samples are tempered at low termperatures for a long time.

Why should I have my ThermoMixer serviced at regular intervals?

Eppendorf offers a selection of preventive maintenance services which ensure a consistent performance of the device and confidence in the results.

How often does my ThermoMixer need to be serviced?

This depends on how intensively it is used and varies depending on the load on the device. However, we recommend to have it serviced at least once a year.

What do you need to look out for before carrying out a service?

The device needs to be decontaminated first. The device must be freely accessible and all samples removed from the device. You should also ensure that the device has cooled down already.

What types of service programs are available for the ThermoMixer?

The available service programs can be found under the respective instrument in the Service & Support / Maintenance and Certification Services section.

What are the costs for the different ThermoMixer service programs?

The cost depends on the model and on the service that is performed. Please contact your local Eppendorf Service.

Please contact your local Eppendorf Service Team. You find the contact data on our homepage or in the information materials.

What is IQ or OQ and what do I need them for?

Installation and operational qualification; the IQ documents that the device has been delivered and installed correctly. The OQ checks the correct functioning of a device. IQ/OQ ensure that your quality management requirements are met and that your device operates properly and in accordance with the manufacturer’s specifications.

How often does the OQ need to be carried out for a ThermoMixer?

The company is responsible for technical checks of devices. Eppendorf recommends regular device qualifications depending on the intensity of use, however, they should be carried out at least once a year.

What does the temperature verification include and how often does it need to be carried out?

To ensure that your ThermoMixer delivers reproducible and correct results, temperature verification and adjustment - if required - are strongly recommended. Temperature verification is a very accurate and precise method and complies with all laboratory requirements with regard to documentation and detection in accordance with national and international standards.

How can temperature accuracy be verified?

The best temperature accuracy possible is ensured by the individual adjustment of each SmartBlock. The Eppendorf Temperature Verification System- Single Channel is used to check the temperature accuracy of the thermoblock. In combination with the temperature sensor for the Eppendorf ThermoMixer, the exact temperature in the thermoblock can be measured. You can find further information in the corresponding operating manual.

How can my device be cleaned and which cleaning agents and disinfectants can be used for cleaning and disinfection of ThermoMixer C, ThermoMixer F and ThermoStat C?

Switch off the device, disconnect the mains/power plug and make sure that no liquid can get into the inside of the housing. When cleaning has been completed, the device should only be connected when it is fully dry on the inside and on the outside. Do not use any aggressive chemicals on the device or its accessories such as strong and weak bases, strong acids, acetone, formaldehyde, halogenated hydrocarbons or phenol. If the device is contaminated with aggressive chemicals, clean it immediately using a mild cleaning agent. Use a lint-free cloth and a mild, soapy laboratory cleaner and distilled water. Clean the housing and the thermoblock regularly. Please refer to your operating manual for further information - Maintenance chapter

What types of training or online training do you offer to enable me to improve my skills?

Please visit the Eppendorf webpage about the Eppendorf Training Center or contact your local Eppendorf Service for further information and a quotation.

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Eppendorf ThermoMixer^® C

ThermoMixer C混匀仪：SmartBlock加热模块，1.5 mL，正面

Mixing a low-volume sample within a 96 well plate

Eppendorf SmartBlock DWP 500 with white DWP

Eppendorf ThermoMixer C with ThemoTop for enhanced temperature accuracy and less condensation within sample tubes

Eppendorf Transfer_Rack_1.5/2.0 mL_用于将样品转从Eppendorf ThermoMixer C中移出

ACT label of sustainability certification for Eppendorf ThermoMixer C

Eppendorf ThermoMixer_C with SmartBlock_15 mL_for sample heating and mixing

Eppendorf ThermoMixer_C with SmartBlock_PCR 96_for incubating PCR plates

An Eppendorf ThermoMixer heats/cools/shakes also larger vessels

ThermoMixer C SmartBlock: plate, total, angle

Eppendorf ThermoMixer C with SamrtBlock and lid

Eppendorf ThermoMixer C with lab scientist who changes the ThermoTop

产品信息

深入了解样品混匀、加热和冷却多功能解决方案。配件包括多种SmartBlock加热模块，如用于样品快速调温的定制型DWP模块、用于无水细胞受控解冻的专用模块、防止容器盖内冷凝水形成的加热盖（ThermoTop^®），以及可独立于主模块在不同温度下培养1.5 ml试管的SmartExterder模块。

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Eppendorf ThermoMixer^® C

主机，不含 Eppendorf 可更换式加热模块
ACT, 220 – 240 V/50 – 60 Hz (CN)

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目录编号 5382000074

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¥ 59,549.00

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技术数据

用途

特征

您的需要，应有尽有。 深入了解样本混匀、加热和冷却多场景应用解决方案——已通过全球数千家实验室测试验证。

了解更多：视频：Eppendorf ThermoMixer^{^®}恒温混匀仪应用广泛

• 多功能一体机：混匀、加热和冷却100 µL – 50 mL离心管、微孔板、深孔板、PCR板及冻存管（无水自动细胞解冻）
• 提升工作板传热效率：深孔板（96 孔、500/1000 µl）与PCR板（96/384 孔）专用贴形温控模块
• 确保模块均匀受热：配有唯一序列号温度检测证书，支持温控模块单独校准，提供IQ/OQ GxP服务
• 优化混匀效果：最高转速3,000 rpm，配3 mm大轨道直径(^2DMix-Control)
• 无工具模块更换，仅需数秒即可完成：采用Eppendorf QuickRelease技术，自动识别温控模块
• 防止离心管内冷凝产生，提高模块温度均匀性：选配ThermoTop^®热盖，根据不同类型SmartBlocks温控模块（≤‌ 2.0 mL）采用不同加热方案
• 不同温度并行孵育：选配SmartExtender扩展架，最多可容纳12 支 1.5 mL离心管，适用于酶促反应
• 加快实验速度：5 个常用程序快捷键，另可保存15 个多参数自定义程序
• 成熟设计，经久耐用：采用耐用设计，配备LCD显示屏——适用于教学实验室，能够可靠运行数年
• 助力可持续发展目标：可持续发展评分通过非政府机构My Green Lab^®审核，并荣获ACT^®环保标签

想要寻找长期可靠的实验室“合作伙伴”？

Eppendorf恒温混匀仪依托近80 年实验室振荡设备研发经验，深受全球数千家实验室信赖。Eppendorf恒温混匀仪经久耐用，不间断运行多年后仍能保持性能稳定。

• 采用耐用设计，配备LCD显示屏——适用于教学实验室，运行稳定可靠
• 无皮带传动技术——无需频繁更换皮带，显著节省成本
• 经妥善维护保养即可持续运行10 年及以上
• 采用高品质材料制成，具备出色的耐化学腐蚀性和抗腐蚀性
• 唯一序列号温度检测证书
• 支持温控模块单独校准
• 提供全球技术与应用支持服务
• 德国汉堡原装制造

样本真正混匀了吗？——^2DMix-Control3 mm轨道直径，最高转速3,000 rpm

在混匀操作中，我们往往默认样本已均匀混合而不作任何验证，因为混匀效果检查较为困难。然而，Eppendorf数十年恒温混匀仪开发经验和客户反馈表明，混匀效果会因参数设置不同而产生巨大差异。^2DMix-Control技术采用可控圆周振荡模式，轨道直径3 mm，最高转速3,000 rpm，尤其适用于微量离心管、工作板或难混匀样本，这些应用场景往往需要大轨道直径配高转速才能实现均匀混合（详见下方链接）。

了解更多：转速和轨道直径对96和384孔板混匀效果的影响

需要实现工作板快速温度传导？——SmartBlocks贴形温控模块

是否测量过样本温度随时间的变化曲线？结果可能会令你大吃一惊：即使温控模块升温或降温速率很快，但样本实际温度仍可能大幅偏离设定温度，且可能需要较长时间才能达到目标温度。
样本温度变化受传热效率影响。离心管专用温控模块能够完全贴合除管盖以外的全部管壁，以此提升传热效率。适配工作板的加热模板目前共有两种：平底款以及类似PCR循环仪的贴形款。
SmartBlocks贴形温控模块适配深孔板（96 孔，500/1000 µl）与PCR板（96/384 孔），可实现快速热传导，即使在较短时长实验中，也能确保样本快速达到设定温度（孵育5 分钟后热像图对比详见右侧）。

提示：若计划使用深孔板或PCR板执行混匀任务，建议实际测量样本温度变化曲线并与目标温度曲线进行对比，或选购贴形温控模块。

无需工具、无需螺丝、无需调节，仅需数秒即可完成模块更换——Quick Release

不想浪费时间拧紧细小螺丝、插拔易损线材、到处寻找配套工具或手动更改模块设置？虽然多款恒温混匀仪都宣称可以“轻松更换温控模块”，但往往从不通过视频展示完整更换流程——原因不言而喻。

Eppendorf开发的Quick Release技术能够真正简化模块更换操作：按压操作杆即可完成SmartBlocks温控模块更换，接着混匀仪便可自动识别新模块。短短几秒就能开展新的混匀实验。

提示：如果后续打算定期更换温控模块，建议在选购恒温混匀仪时查阅产品说明书或尝试亲自更换。你会惊讶地发现温控模块的更换难易程度天差地别，具体取决于所选品牌或机型。

视频：1、2、完成—— SmartBlock 温控模块更新就是如此迅速

样本浓度长时间保持稳定，且处于温控模块不同位置的样本之间具有可比性——ThermoTop热盖

离心管内部可能因温度、时间和转速等产生冷凝水，造成样本浓度波动。随着冷凝水珠形成并滴落至样本中，样本浓度可能无法长时间保持稳定。若进一步对比温控模块中心位置与边缘位置的离心管或孔井，情况会更加复杂。因此，冷凝现象会加大实验结果偏差，需要增加实验次数才能取得具有统计显著性的结果。
选配ThermoTop热盖可根据不同类型SmartBlocks（不超过2.0 mL）采用不同加热方案，无需手动调节即可有效防止冷凝产生，避免样本过热；同时确保样本长时间保持浓度稳定，进一步提升不同热块位置间样本的可比性。

提示：建议选购一款配备热盖且具备自动模块识别功能以及微量离心管或不同类型工作板自动适配功能的恒温混匀仪。手动调节高度或温度不仅耗时费力，还可能导致无法及时察觉样本过热。

了解更多： ThermoTop热盖的冷凝防护作用

不同温度同步孵育——SmartExtender

想要更加自由灵活？何不考虑两个不同温度同时孵育？或将孵育容量提升50 %（1.5 mL离心管）？
SmartExtender扩展架最多可容纳12 支 1.5 mL离心管，适配全系Eppendorf SmartBlocks温控模块，能够实现37 °C与95 °C酶促反应同步进行。采用独立加热设计，可与Eppendorf SmartBlock温控模块搭配使用，同时保留其加热、冷却和混匀功能。

离心管轻松转移，反应同步启动——Transfer Rack

需要在60秒内同时完成24 份样本孵育？Eppendorf Transfer Rack转存架可将24 支离心管一次性移入Eppendorf SmartBlock温控模块或从中取出，整体操作安全便捷，确保所有样本的反应条件完全一致。适配SmartBlock温控模块（0.5 mL、1.5 mL、2.0 mL），标配Transfer Rack转存架。最多可容纳24 支微量离心管，实现高温离心管便捷转移，杜绝烫伤风险。

提示：可借助Transfer Rack转存架盖快速倒置所有离心管，或通过轻按确保所有离心管妥善放置于SmartBlock温控模块内。

大幅优化PCR实验流程

除可适配96孔和384孔PCR板的SmartBlocks温控模块以及具备高效热传导功能的ThermoTop^{^®}热盖（见上文）外，Eppendorf还推出了多款其他配件，能够满足各类混匀操作要求。

• 叠放式PCR-Rack
• PCR-Cooler低温指示冰盒（粉色/蓝色）：确保96孔PCR板在0 °C下持续保冷超过1小时（提前预冷2 小时，预冷温度-20 °C），并在温度超过7 °C时变色指示（从下到上颜色变化详见右图）

想要加快实验速度？

不想花费时间调取程序或费力为实验室新成员开展恒温混匀仪全面培训？
按下快捷键即可启动5个预设程序之一，也可自行创建专属程序（共可存储15 个多参数自定义程序）。配备直观用户操作界面，支持5种操作语言。

助力实现可持续发展目标

Eppendorf恪守ACT^®环保标签强调的问责制、一致性和透明度三大原则，致力于持续降低环境影响，为客户提供高品质、可持续产品。
除推出多款环保产品外，Eppendorf可持续发展评分已通过非政府机构My Green Lab^®认证审核，Eppendorf ThermoMixer^® C恒温混匀仪也已荣获ACT环保标签。

了解更多： Eppendorf ThermoMixer C恒温混匀仪的可持续设计

是否为不舒服的操作方式困扰？

人体工程学并非仅限于“人体工程学座椅”。Eppendorf早在20世纪70年初，便已开始从人体工学角度优化实验室设备。
2003年，我们正式推出PhysioCare Concept^®设计理念，着力改进移液器等液体处理设备的人体工学设计。
如今，Eppendorf PhysioCare Concept理念已覆盖更多实验室设备品类，旨在打造兼顾实验室工作流程与实验人员健康及操作舒适度的一体化解决方案。以Eppendorf ThermoMixer恒温混匀仪为例：
• 采用Eppendorf QuickRelease技术，实现温控模块快速、轻松更换
• 隔热式SmartBlock温控模块，确保安全取放，杜绝手指烫伤
• 直控按键，操作便捷
• 小巧机身，可轻松置于实验台手臂可及范围之内
• 标准化用户界面设计，操作直观

了解更多：Eppendorf PhysioCare Concept

VisioNize^®

不止保护样本安全

Lab Suite

随时随地掌握实验室核心数据。VisioNize Lab Suite为实验室设备提供可靠的数字化监控解决方案，助您提升样本安全、满足合规要求。
实时监控温度、转速和设备交互等所有关键参数。随时掌握实验进程，并通过APP、电子邮件或短信即时接收程序结束等重要事件通知。
轻松导出参数与事件日志用于存档记录或数据分析，满足合规及研究要求。
持续监测与实时预警，让实验管理省心更放心。

了解有关VisioNize Lab Suite的更多信息，助力实验室实现数字化转型！

包装处置

混匀仪包装包含不同材料，包括纸板、塑料防尘罩和一些泡沫部件。材料的回收变得越来越重要：您知道欧洲几乎回收所有的纸板材料吗？我们的混匀仪纸板包装含有约 60 %的回收材料。请收集仪器包装材料并将其放置在贵公司的适当收集容器中，以实际行动支持回收有价值原材料的全球可持续性倡议。对于采用低密度聚乙烯（LD-PE）制成的塑料防尘罩和泡沫部件，建议选择一家专门回收聚乙烯材料的合作伙伴。请联系当地废物管理公司或设施管理团队，了解贵公司的可用回收方案。

仪器处置
我们的混匀仪可以使用多年。但是，如果需要更换，我们建议您根据当地要求，妥善处置相关仪器。我们强烈推荐选择拥有电子仪器回收经验且经过认证的本地回收合作伙伴。“本地”处理可减少运输影响。由于某些部件需要以安全、可持续的方式进行移除和回收，因此建议采用“认证”方式对其进行处置。

去污
该设备用于实验室和/或用于处理生物样品。请记住对需要处理的设备进行充分去污。查看当地要求。有关更多信息，请联系当地的生物安全官员和/或废物管理官员。检查您当地的回收合作伙伴是否有特殊说明和/或文件要求。您也可以使用Eppendorf去污表格作为指导。

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规格	Eppendorf ThermoMixer^® C

ACT 标签	是
样品容量	5 µL 至 50 mL 的所有常见离心管和工作板
产品类型	ThermoMixer 恒温混匀仪
定时器	5 秒至99:30 小时, 可连续运行
接口	USB 接口
电源	220 – 240 V, 50 – 60 Hz
最大能耗	200 W
尺寸（长x宽x高）	20.6 × 30.4 × 13.6 cm / 8.1 × 12.0 × 5.4 in
产品重量	6.3 kg / 13.9 lb
最大速度	3,000 rpm，¹⁾
温度范围	最低温度：环境温度以下 15 °C 最高温度： 100 °C²⁾
混匀频率	300 – 3,000 rpm，¹⁾
混合和漩涡半径	1.5 mm
最低和最高温度设定	1 °C/100 °C
振幅	3 mm
温控准确性	最快 20 - 45 ±0.5 °C，²⁾

Eppendorf ThermoMixer^®
升温速率	最快 7 °C/分钟（使用SmartBlock板时）¹⁾
冷却速率	最大 2.5 °C/分钟，100 °C 和室温之间