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BioFlo® 320 plus

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Información del producto

The BioFlo 320 plus is a universal bench-scale bioreactor system engineered to enable seamless process transfer from R&D to clinical and commercial manufacturing. Powerful technology for precise process monitoring and control, a large working volume range, the interchangeability of glass and BioBLU® Single-Use Bioreactors, and software tools that save time, reduce risks, and enable powerful data analysis make it a reliable partner for developing robust processes and scaling them up from R&D to manufacturing. It is suitable for cell culture as well as microbial applications.

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Productos (2)

Accesorios (12)


    BioFlo® 320
    • estación de control base
    • con conexión de agua
    Más detalles del producto ...
    N.o de catálogo 1379963011

      BioFlo® 320
      • estación de control base
      • sin conexión de agua
      Más detalles del producto ...
      N.o de catálogo 1379962911

      Información del producto
      Aplicaciones
      Características

      The BioFlo 320 plus seamlessly connects R&D to clinical and commercial manufacturing


      The BioFlo 320 plus is compatible with a wide selection of bioreactors, providing working volumes from 400 mL to 40 L on a single platform. In combination with the BioFlo 720 bioreactor control system, the BioFlo platform supports one of the widest range of single-use solutions, allowing the scale-up of your process to up to 500 L.
      • Validation Guide available to support controller qualification for manufacturing applications.
      •  In combination with BioBLU HNQ Single-Use Bioreactors, DASware® control plus SCADA software, and service offerings for qualification and calibration, the BioFlo 320 plus provides a unified solution to support compliance with GMP requirements.
      • Integrated Scale Up Assist software feature simplifies the calculation of important process parameters necessary to scale up and down.
      • Emerson® DeltaV integration with the BioFlo 320 plus simplifies tech-transfer, scale-up, and recipe sharing.

      The BioFlo 320 plus is highly configurable to suit your requirements


      The BioFlo 320 plus offers the highest level of application flexibility, made possible by features like universal connections for analog and digital sensors, up to six integrated pumps, a highly configurable gas flow control, and compatibility with a wide range of glass and single-use bioreactors.
      • Suitable for the cultivation of human and animal cells, including stem cells, as well as microbial fermentation.
      • Supports batch, fed-batch, continuous, and perfusion mode.
      • Suitable for many applications, including the production of cells, secreted proteins, viral vectors, plasmids, and small molecules.


      Eppendorf Bioprocess Products – application in GMP regulated environment
      Download document to find out which features you can expect at minimum from Eppendorf products that are deemed suitable or compatible for GMP.

      Precise and user-friendly process control with integrated software features


      Integrated software features let you control your process precisely, and help you save time and mitigate risks.
      • Automatic gas mixing algorithms for simplified control (4-gas, 3-gas) in cell culture applications.
      • O2 enrichment and N2 enrichment to optimize the gas supply in microbial applications.
      • Ten-point cascade feature for sophisticated control strategies.
      • Built-in elapsed fermentation timer for batch management.
      • Trend display with up to twelve process values within a single view.
      • The diagnostic screen provides information on the hardware status and upcoming maintenance.
      • Auto Calibrate software feature: automatic calibration of all connected DO sensors at once reduces preparation time and ensures consistence.
      • Integrated Scale Up Assist software feature simplifies the calculation of important process parameters necessary to scale up and down.

      Further advance process control and analytics by connecting to Bioprocess SCADA software


      Integrate your BioFlo 320 plus with DASware control SCADA software for even more possibilities to save time, mitigate risks, and turn bioprocess data intro actionable insights.
      • Advance process control: Use of the DASware software suite offers advanced features for process control, such as the integration of external sensors and scripting of feedback loops.
      • Turn data into knowledge: All data collected by DASware control can be visualized seamlessly in BioNsight cloud software. This enables you to monitor running processes in real-time, share data across runs, sites, and scales, and leverage hybrid-modelling technology to understand your process better with less experiments.
      • Automate bioprocess sampling: Short and regular sampling intervals help obtaining strong datasets and optimizing process control. Integrate the BioFlo 320 plus with the Bioprocess Autosampler for automated sampling 24/7 and gaining better data with less effort.
      • Use in clinical and commercial manufacturing: To be used in clinical and commercial manufacturing, the BioFlo 320 plus can be connected to the DASware control plus SCADA software. This is compatible to 21 CFR Part 11 and EudraLex Volume 4 Annex 11, offers user authentication and access control, as well as electronic records and signatures.

      Collect the data you need with intelligent sensors


      The BioFlo 320 plus is compatible with a wide range of sensors to enable you to collect the process data you need while reducing the risk of sensor failure.
      • Integrated Mettler Toledo Intelligent Sensor Management (ISM) and Hamilton ARC platform
      • Universal connections for up to four analog or digital (ISM/ARC) sensors
      • pH: analog or digital (ARC/ISM)
      • DO: analog or digital (ARC/ISM)
      • Optical DO: digital (ARC/ISM)
      • Redox: analog or digital (ISM)
      • CO2: digital (ISM)
      • Real-time sensor diagnostics anticipate sensor failure

      Save lab space with a small controller footprint


      From R&D laboratories to pilot-scale production facilities, space is an important factor when selecting the right equipment. The BioFlo 320 plus offers flexibility, better control, and maximum functionality while occupying a fraction of the valuable lab space of similar systems. This means greater efficiency and productivity at a lower operating cost for your lab.