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- Forum Labo 2025
- Advanced Therapies Week (ATW) 2025
- SLAS Europe 2025
- Bioprocessing Summit Europe 2025
- Medlab Middle East 2025
- SLAS International 2025
- Biologics World Nordics 2025
- ASIA LABEX: The Lab Show 2025
- BioProcess International Europe 2025
- ISEV 2025
- CBioPC 2025
- Future Labs Live 2025
- Cell 2025
- ASIA LABEX: The Lab Show 2025
- Stem Cell Community Day 2025
- JASIS 2025
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BioFlo® 320 for commercial manufacturing
BioFlo 320 with BioBLU 50c and scale
BioFlo 320 兼容 250 mL - 40 L BioBLU 一次性使用罐体。
产品信息
The BioFlo 320 is a universal bench-scale bioreactor system for both process development and clinical and commercial manufacturing. Powerful technology for precise process monitoring and control, a large working volume range, and software features that save time and reduce risks make it a reliable partner for developing robust processes and scaling them up from R&D to manufacturing. It is suitable for cell culture as well as fermentation application.您可以在以下网址找到其他下载资料本页面底部
产品信息
用途
特征
产品信息
The BioFlo 320 seamlessly connects R&D to clinical and commercial manufacturing
The BioFlo 320 is compatible with a wide selection of bioreactors, providing working volumes from 400 mL to 40 L on a single platform. In combination with the BioFlo 720 bioreactor control system, the BioFlo platform supports one of the widest range of single-use solutions, allowing the scale-up of your process to up to 500 L.
• Validation Guide available to support controller qualification for manufacturing applications.
• In combination with BioBLU HNQ Single-Use Bioreactors, DASware control plus SCADA software, and service offerings for qualification and calibration, the BioFlo 320 provides a unified solution to support compliance with GMP requirements.
• Integrated Scale Up Assist software feature simplifies the calculation of important process parameters necessary to scale up and down.
• Emerson® DeltaV integration with the BioFlo 320 simplifies tech-transfer, scale-up, and recipe sharing.
The BioFlo 320 is highly configurable to meet your application needs
Advanced technical features make the BioFlo 320 a powerful tool for R&D as well as manufacturing. A high level of application flexibility is made possible by features like universal connections for analog and digital sensors, up to six integrated pumps, a highly configurable gas flow control, and compatibility with a wide range of glass and single-use bioreactors.
• Suitable for the cultivation of human and animal cells, including stem cells, as well as microbial fermentation.
• Supports batch, fed-batch, continuous, and perfusion mode.
• Suitable for many applications, including the production of cells, secreted proteins, viral vectors, plasmids, and small molecules.
Eppendorf Bioprocess Products – application in GMP regulated environment
Download document to find out which features you can expect at minimum from Eppendorf products that are deemed suitable or compatible for GMP.
The BioFlo 320 is compatible with a wide selection of bioreactors, providing working volumes from 400 mL to 40 L on a single platform. In combination with the BioFlo 720 bioreactor control system, the BioFlo platform supports one of the widest range of single-use solutions, allowing the scale-up of your process to up to 500 L.
• Validation Guide available to support controller qualification for manufacturing applications.
• In combination with BioBLU HNQ Single-Use Bioreactors, DASware control plus SCADA software, and service offerings for qualification and calibration, the BioFlo 320 provides a unified solution to support compliance with GMP requirements.
• Integrated Scale Up Assist software feature simplifies the calculation of important process parameters necessary to scale up and down.
• Emerson® DeltaV integration with the BioFlo 320 simplifies tech-transfer, scale-up, and recipe sharing.
The BioFlo 320 is highly configurable to meet your application needs
Advanced technical features make the BioFlo 320 a powerful tool for R&D as well as manufacturing. A high level of application flexibility is made possible by features like universal connections for analog and digital sensors, up to six integrated pumps, a highly configurable gas flow control, and compatibility with a wide range of glass and single-use bioreactors.
• Suitable for the cultivation of human and animal cells, including stem cells, as well as microbial fermentation.
• Supports batch, fed-batch, continuous, and perfusion mode.
• Suitable for many applications, including the production of cells, secreted proteins, viral vectors, plasmids, and small molecules.
Eppendorf Bioprocess Products – application in GMP regulated environment
Download document to find out which features you can expect at minimum from Eppendorf products that are deemed suitable or compatible for GMP.
集成 智能传感器
• Mettler Toledo智能传感器管理(ISM)平台
• 配备通用接口,可以同时连接四个模拟或数字传感器
• pH:模拟或数字(ISM)
• DO:模拟或数字(ISM)
• 光学DO:数字(ISM)
• 氧化还原:模拟或数字(ISM)
• CO 2: 数字(ISM)
• 实时传感器诊断可预测传感器故障
连接DASware control plus控制软件
为应用于临床和商业生产, BioFlo 320可以连接功能强大的DASware control plusSCADA软件。
• 符合21 CFR Part 11与EudraLex第4卷附录11相关规定
• 用户身份验证与访问控制
• 电子记录与签名
使用DASware软件套件可为过程控制带来更多先进功能,如集成外部传感器、反馈回路脚本撰写。
先进软件解决方案有助节省时间并降低风险
• 通过单一用户界面同时控制最多八台设备
• 自动气体混合算法,简化气体控制(4-gas,3-gas)、增O2、增N2流程
• 十点级联,能够实施复杂的控制策略
• 警报功能,可通过控制器上的警报历史概览自动通报工艺状态,也可在警报发生时向用户发送电子邮件。
• 诊断屏幕显示硬件状态信息和下次维护信息。
• 自动校准——一次性自动校准所有连接的溶氧传感器,能够显著缩短准备时间、确保一致性。
无缝数据获取,增进协作
由DASware control 采集的所有数据均可通过BioNsight cloud软件实现无缝可视化。
便于用户实时跟踪和监测运行过程,并对运行过程进行远程分析。
• 实时监测所有运行过程。
• 与黄金批次运行进行对比。
• 跨实验室、站点甚至合作伙伴共享数据。
• 利用混合建模技术加快关键质量属性预测速度、大幅减少实验次数。
占地面积小
从研发实验室到中试生产工厂,所占空间大小是挑选合适设备时的一项重要考量因素。BioFlo 320应用灵活、控制出色、功能完善,但其占地面积较同类产品大幅减少,有助节省实验室宝贵空间。从而让您的实验室运行成本更低、效率和生产力更高。
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用途
- Universal bench-scale controller for cell culture and fermentation applications in R&D and clinical and commercial manufacturing
- Fermentation of aerobic and anaerobic bacteria, yeasts, and fungi
- Cultivation of mammalian, insect, and human cell lines
- Cultivation of stem cells
- Specialized packed-bed impeller for the cultivation of anchorage and non-anchorage dependent cells, for example for vaccine process development
- Cell culture on microcarriers using specialized cell-lift impeller
- Suitable for batch, fed-batch, and continuous/perfusion processes
- Validation Guide available to support controller qualification for manufacturing applications1)
特征
- Universal control for both microbial and cell culture applications
- Controls up to eight systems from a single user interface
- Compatible with BioBLU HNQ Single-Use Bioreactors
- Up to six integrated pumps capable of operating in variable-speed mode
- Integrated Mettler Toledo® ISM® platform
- Built-in optical pH sensing technology for use with the BioBLU HNQ Single-Use Bioreactors
- Field-upgradable TMFC drawers for sparge and overlay gas
- Eight independently controlled process gas supplies
- Enhanced software package with new cascade and time profile features
- DeltaV compatibility available through DeltaV Discovery and DeltaV ProPlus PAS
- Validation Guide available to support controller qualification for manufacturing applications.
- Compatible with 21 CFR Part 11 and EudraLex Volume 4 Annex 11 compatible DASware control plus SCADA software