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Monoclonal Antibody Production
mAB discovery workflow
Antibody development is not without its challenges. Research teams are under increasing pressure to produce specific, high-quality therapeutic treatments within ever-tighter time and budget restrictions. As such, it is essential to optimize each step of the monoclonal antibody production process, from transfection, to clone selection, to process control and scale-up. From choosing candidate cell lines to scale-up, Eppendorf can help you to maintain a competitive edge by providing the tools, expertise, and knowledge needed to improve and regulate antibody yield and quality.
Choose the right bioreactor system for monoclonal antibody production
Parallel, small-scale bioprocess systems
Parallel small-scale bioreactor systems like the DASbox
Eppendorf offers a scalable portfolio of single-use bioreactors, for seamless process scale-up from R&D labs to pilot production facilities.
- The BioBLU® c Single-Use Bioreactors cover a working volume range of 100 mL to 40 L. These are rigid wall, stirred-tank bioreactors, which are compatible with various Eppendorf bioreactor control systems, including the DASbox
®Mini Bioreactor System , the SciVario ®twin , and the BioFlo ®320 bioreactor control system .
- For scale-up to larger volumes Eppendorf offers the BioFlo
®720 bioreactor control system , which is compatible with Thermo Scientific™ HyPerforma™ 5:1 single-use bioreactors with a working volume up to 2000 L.
From small scale to pilot production scale
Bioprocess scale-up from small development scale to pilot scale is a fundamental part of process development in the biopharmaceutical industry. Eppendorf provides upstream bioprocess solutions that make it simple to scale up your antibody production. Small and bench-scale bioreactors, including the DASbox
Eppendorf bioprocess software including DASware