Anchorage-dependent cells, such as Vero cells, are widely used as a platform for viral vector production. To cultivate Vero cells in stirred-tank bioreactors, they require a growth matrix to attach to. The development of processes at bench scale is crucial to establish cost-efficient workflows in larger volumes. In this webinar, we demonstrate, how different process parameter can be monitored and controlled in a perfusion bioprocess to cultivate anchorage-dependent cells. We demonstrate the great potential of using packed-bed bioreactors or microcarrier spin filter for attachment cell-based vaccine production.
Key Learning Objectives:
- Importance of high-quality pre-cultures for bioreactor inoculation
- Importance of process monitoring and control
- Hands-on expertise on how to cultivate and grow anchorage dependent cells on different attachment matrixes.
Who Should Attend:
- Experienced scientists looking for tips and tricks to improve their processes
- Scientists that are looking for solutions to produce enough material for the inoculation of large pilot and production sized bioreactors
- Scientists who are interested in the cultivation of anchorage-dependent cells in stirred-tank bioreactors
Date & Time:
Thursday, October 22, 2020 at 10am EDT| 9am CDT| 3pm BST| 4pm CEST
Durtion: 1 hour
Michelet Dorceus, Bioprocess Field Application Manager, Eppendorf North America