CAR-T Cell Research and Development

Well thought-out tools for pharmaceutical and biotech laboratories

CAR-T Cells: Breakthroughs in Cancer and Auto-Immune Therapies

One of the most revolutionary cell therapies to transition from bench to bedside in the past decade is undoubtedly the development of chimeric antigen receptor (CAR)-T cells. Here, CAR-T cells have found a plethora of different applications. Firstly, by proving to be an effective treatment for certain blood cancers that were previously deemed incurable. Secondly, in holding promise for treating certain auto-immune diseases and solid tumours.

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Product Solutions for the CAR-T Cell Research Workflow

As ongoing research broadens the applications of CAR-T cells, the potential for
transformative outcomes continuous to grow.

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Product Solutions for the Lentivirus Vector Production Workflow

Lentiviral vectors, originally derived from the HIV-1 retrovirus, are a popular vehicle for delivering genetic material in cell and gene therapy.

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Product Solutions for the AAV Vector Production Workflow

A revolutionary vehicle that is used in research to deliver genetic material in cell and gene therapy is the adeno-associated virus (AAV).

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CAR-T Cell Development – The Future of Fighting Cancer

CAR-T cells, genetically engineered and equipped with specific receptors to target and combat cancer cells, are primarily divided into two categories: autologous and allogenic CAR-T cells. Hereby, autologous CAR-T cells derive from the patient’s own white blood cells and are reintroduced after modification, whereas allogenic CAR-T cells are designed as off-the-shelf solutions for use in different patients. However, both approaches have their challenges. The manufacturing process for autologous CAR-T cells is complex and costly, as each patient’s cells must be individually processed. Allogeneic CAR-T cells, on the other hand, currently do not have the same safety profile, necessitating further research to address these issues.

Supporting you – maintenance and qualification services

With our basket of Service and Extended Warranty Agreement solutions we take the load off your shoulders by simplifying your ordering and budgeting process for various services over the full lifetime of your instruments.

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Sustainability can only be achieved in collaboration

The fundamental principle of sustainability has always played a role at our company since its founding in 1945. Within the Eppendorf Group, our goal is to continue to grow and develop so that we do not exceed the bounds of our planet’s resilience now or in the future, and to ensure that our actions are aligned with society’s needs.

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Shift the paradigm – best-fit solutions for CAR-T cell research

CAR-T research has to meet stringent quality standards and must be done quickly and cost-effectively. Eppendorf’s best fit solutions are tailored to the individual needs of your CAR-T development workflow.

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