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- Challenges and Chances: A Review of the 1st Stem Cell Community Day
- Summertime, and the Livin’ Is Easy…
- Follow-on-Biologics – More than Simple Generics
- Bacteria Versus Body Cells: A 1:1 Tie
- Behind the Crime Scene: How Biological Traces Can Help to Convict Offenders
- Every 3 Seconds Someone in the World Is Affected by Alzheimer's
- HIV – It’s Still Not Under Control…
- How Many Will Be Convicted This Time?
- Malaria – the Battle is Not Lost
- Physicians on Standby: The Annual Flu Season Can Be Serious
- At the Forefront in Fighting Cancer
- Molecular Motors: Think Small and yet Smaller Again…
- Liquid Biopsy: Novel Methods May Ease Cancer Detection and Therapy
- They Are Invisible, Sneaky and Disgusting – But Today It’s Their Special Day!
- How Many Cells Are in Your Body? Probably More Than You Think!
- What You Need to Know about Antibiotic Resistance – Findings, Facts and Good Intentions
- Why Do Old Men Have Big Ears?
- The Condemned Live Longer: A Potential Paradigm Shift in Genetics
- From Research to Commerce
- Chronobiology – How the Cold Seasons Influence Our Biorhythms
- Taskforce Microbots: Targeted Treatment from Inside the Body
- Eyes on Cancer Therapy
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- Challenges and Chances: A Review of the 1st Stem Cell Community Day
- Summertime, and the Livin’ Is Easy…
- Follow-on-Biologics – More than Simple Generics
- Bacteria Versus Body Cells: A 1:1 Tie
- Behind the Crime Scene: How Biological Traces Can Help to Convict Offenders
- Every 3 Seconds Someone in the World Is Affected by Alzheimer's
- HIV – It’s Still Not Under Control…
- How Many Will Be Convicted This Time?
- Malaria – the Battle is Not Lost
- Physicians on Standby: The Annual Flu Season Can Be Serious
- At the Forefront in Fighting Cancer
- Molecular Motors: Think Small and yet Smaller Again…
- Liquid Biopsy: Novel Methods May Ease Cancer Detection and Therapy
- They Are Invisible, Sneaky and Disgusting – But Today It’s Their Special Day!
- How Many Cells Are in Your Body? Probably More Than You Think!
- What You Need to Know about Antibiotic Resistance – Findings, Facts and Good Intentions
- Why Do Old Men Have Big Ears?
- The Condemned Live Longer: A Potential Paradigm Shift in Genetics
- From Research to Commerce
- Chronobiology – How the Cold Seasons Influence Our Biorhythms
- Taskforce Microbots: Targeted Treatment from Inside the Body
- Eyes on Cancer Therapy
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Centrifuge Solution for Monoclonal Antibody Discovery
Centrifugation is part of all mAb workflow steps! Eppendorf‘s Centrifuge Solutions keep up with all demands – compiled to fit highly specific needs of each step, method and sample type. Cope efficiently with various vessel formats, volumes and repetitive centrifugation steps. Master high-throughput and cell culture applications. Handle temperature-sensitive and valuable samples safely and reproducibly. Minimize interaction periods with fast and easy to handle devices and keep processes running. From hit generation and screening up to transfer to production - our solutions are made for optimal centrifugation to produce fast and reliable results!

Discover the centrifuge workflow solutions
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Hit to Lead Discovery
Production of Target Antigen
MOLECULAR BIOLOGY SOLUTION
Plasmid construction (small) | Sequencing preparation | Humanization (small)
- Safe centrifugation with open tube lids
- Fast and easy operation: QuickLock® rotor, short key function, automatic lid opening
- Minimal noise pollution: optimized sound design

HIGH SPEED SOLUTION
Plasmid construction (large) | Lysate clarification | Humanization (large)
- Fast and easy operation: favorite functions accessible within seconds, QuickLock® rotor
- Optimal cooling for sample integrity

BIG VOLUME HARVESTING SOLUTION
Expression in bacteria and cell lines | Antibody expression
- For large volume suspensions
- Optimal cooling for cell integrity
- Cross-contamination risk reduction
- GxP documentation support

VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation

Generation of Hits and Identification
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation

HIGH-THROUGHPUT SCREENING SOLUTION
High-throughput screeing
- Easy and safe plate handling: high-capacity plate carrier, closed plate buckets
- Fast operation: automated, quick pre-cooling

Characterization of Hits and Selection of Leads
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation

LOW-THROUGHPUT SCREENING SOLUTION
Screening assays | Sequencing (spin down)
- Space saving: very small footprint
- Fast parameter changes
- Easy and safe operation: Fast access to your most frequently used settings, automatic lid opening

Lead Optimization
Characterization of Leads
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation

LOW-THROUGHPUT SCREENING SOLUTION
Screening assays | Sequencing (spin down)
- Space saving: very small footprint
- Fast parameter changes
- Easy and safe operation: Fast access to your most frequently used settings, automatic lid opening

MOLECULAR BIOLOGY SOLUTION
Plasmid construction (small) | Sequencing preparation | Humanization (small)
- Safe centrifugation with open tube lids
- Fast and easy operation: QuickLock® rotor, short key function, automatic lid opening
- Minimal noise pollution: optimized sound design

Protein Engineering of Antibody Leads
MOLECULAR BIOLOGY SOLUTION
Plasmid construction (small) | Sequencing preparation | Humanization (small)
- Safe centrifugation with open tube lids
- Fast and easy operation: QuickLock® rotor, short key function, automatic lid opening
- Minimal noise pollution: optimized sound design

HIGH SPEED SOLUTION
Plasmid construction (large) | Lysate clarification | Humanization (large)
- Fast and easy operation: favorite functions accessible within seconds, QuickLock® rotor
- Optimal cooling for sample integrity

Transient Antibody Leads Expression
BIG VOLUME HARVESTING SOLUTION
Expression in bacteria and cell lines | Antibody expression
- For large volume suspensions
- Optimal cooling for cell integrity
- Cross-contamination risk reduction
- GxP documentation support

Candidate Validation
In Vitro Validation
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation

LOW-THROUGHPUT SCREENING SOLUTION
Screening assays | Sequencing (spin down)
- Space saving: very small footprint
- Fast parameter changes
- Easy and safe operation: Fast access to your most frequently used settings, automatic lid opening

Cell Line Development
Classic Cell Culture Solution
Establishment of stable cell line
- Small footprint: optimal size to capacity ratio
- Sample & cross contamination risk reduction: aerosol-tight bucket caps
- Optimal ergonomics with low access height and soft touch lid

Centrifuge Service
Guarantee a safe working environment by regular maintenance as part of your quality management, and ensure that technical specifications comply with the manufacturer's specifications. With our maintenance,, calibration and qualification services, including GxP compliant documentation, you assure consistent instrument performance and safety and you are well prepared for audits.

Request your individual support
Request your individual support
Your own dedicated expert assists you in finding the perfect match for your specific mAb workflow. Get your individual consultation!
Read more
Read less